Fig. 4From: SERPINE1 associated with remodeling of the tumor microenvironment in colon cancer progression: a novel therapeutic targetScreening of immune-related proteins. A A protein-protein interaction network (PPI) was constructed with an interaction confidence value > 0.95. B The top 30 genes with the most nodes and their sub-nodes. C Following univariate COX regression analysis on 1199 genes, a list of the candidate genes is displayed using a significance factor of p < 0.1. D Venn diagram showing the hub genes after the top 100 genes from PPI were matched to the top 24 genes as determined by the univariate COX regressionBack to article page