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Table 1 Clinical and pathological features in patients with gastric and gastroesophageal junction adenocarcinoma, stratified by receipt of preoperative radiation therapy

From: Neo-adjuvant radiation therapy provides a survival advantage in T3-T4 nodal positive gastric and gastroesophageal junction adenocarcinoma: a SEER database analysis

Variables

No NRT

NRT

P

N

3288 (62.4%)

1984 (37.6%)

 

Age (years)

62.0 ± 12.4

61.4 ± 10.2

0.01

Male (%)

2106 (64.1%)

1655 (83.4%)

<  0.001

Year of diagnosis

  

<  0.001

 2004–2009

1321 (40.2%)

646 (32.6%)

 

 2010–2015

1967 (59.8%)

1338 (67.4%)

 

Race/Ethnicity

  

<  0.001

 Non-Hispanic White

1487 (45.2%)

1637 (82.5%)

 

 Black

431 (13.1%)

73 (3.7%)

 

 Hispanic White

692 (21.0%)

153 (7.7%)

 

 Asian/Pacific Islanders

618 (18.8%)

95 (4.8%)

 

 American Indian/Alaska Native

43 (1.3%)

25 (1.3%)

 

 Unknown

17 (0.5%)

1 (0.1%)

 

Tumor differentiation

  

<  0.001

 Well differentiated

71 (2.2%)

86 (4.3%)

 

 Moderately differentiated

659 (20.0%)

649 (32.7%)

 

 Poorly differentiated

2323 (70.7%)

1007 (50.8%)

 

 Undifferentiated

59 (1.8%)

37 (1.9%)

 

 Unknown

176 (5.4%)

205 (10.3%)

 

Tumor size

  

<  0.001

  ≤ 3 cm

755 (23.0%)

534 (26.9%)

 

 3.1–5 cm

808 (24.6%)

552 (27.8%)

 

  > 5 cm

1273 (38.7%)

422 (21.3%)

 

 Unknown

452 (13.7%)

476 (24.0%)

 

Location

  

<  0.001

 Cardia

783 (23.8%)

1833 (92.4%)

 

 Fundus

118 (3.6%)

8 (0.4%)

 

 Body

343 (10.4%)

24 (1.2%)

 

 Antrum

753 (22.9%)

32 (1.6%)

 

 Pylorus

124 (3.8%)

5 (0.3%)

 

 Less curvature

383 (11.6%)

33 (1.7%)

 

 Greater curvature

145 (4.4%)

9 (0.5%)

 

 Overlapping/NOS

639 (19.4%)

40 (2.0%)

 

Lauren classification

  

<  0.001

 Intestinal

1988 (60.5%)

1607 (81.0%)

 

 Diffuse

1083 (32.9%)

271 (13.7%)

 

 Unclassified

217 (6.6%)

106 (5.3%)

 

No. of LNs examined

  

<  0.001

  < 15

1225 (37.3%)

1065 (53.7%)

 

  ≥ 15

2063 (62.7%)

919 (46.3%)

 

Pathologic T stage

  

<  0.001

 T1

357 (10.9%)

195 (9.8%)

 

 T2

1762 (53.6%)

1116 (56.3%)

 

 T3

854 (26.0%)

590 (29.7%)

 

 T4

315 (9.6%)

83 (4.2%)

 

Pathologic N stage

  

<  0.001

 N0

897 (27.3%)

643 (32.4%)

 

 N1

1459 (44.4%)

1129 (56.9%)

 

 N2

629 (19.1%)

183 (9.2%)

 

 N3

303 (9.2%)

29 (1.5%)

 

AJCC 8th TNM stage

  

<  0.001

 I

835 (25.4%)

543 (27.4%)

 

 II

1661 (50.5%)

1265 (63.8%)

 

 III

792 (24.1%)

176 (8.9%)

 

Surgery type

  

<  0.001

 Partial gastrectomy

1980 (60.2%)

1150 (58.0%)

 

 Near total/total gastrectomy

1091 (33.2%)

409 (20.6%)

 

 Gastrectomy, NOS

217 (6.69%)

425 (21.4%)

 
  1. Cohort size, n = 5272. Categorical values are shown as n (%). Continuous variables are shown as mean ± standard deviation