Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells

BMC Cancer

Table 1 The relationship of FMNL2 and clinicopathological variables in breast cancer tissues

Variables	Total No. of patients (n = 114)	FMNL2 expression		χ²	P-value
Variables	Total No. of patients (n = 114)	Negative (n = 80)	Positive (n = 34)	χ²	P-value
Age				1.565	0.211
< 50	65	47	18
≥ 50	49	30	19
histopathological type				0.814	0.665
Invasive ductal carcinoma	111	78	33
Ductal carcinoma in situ	2	1	1
Invasive lobular carcinoma	1	1	0
Clinical stage				5.48	0.065
1	14	12	2
2	48	37	11
3	52	31	21
TNM phase				0.329	0.567
I-II	65	47	18
III-IV	49	33	16
Ki67				11.668	0.001*
< 14%	44	39	5
≥ 14%	70	41	29
Tumor size				0.495	0.482
< 2 cm	32	24	8
≥ 2 cm	82	56	26
ER status				6.327	0.012*
ER (−)	29	15	14
ER (+)	85	65	20
PR status				2.173	0.14
PR (−)	42	26	16
PR (+)	72	54	18
HER2 status				0.31	0.578
HER2 (−)	36	24	12
HER2 (+)	78	56	22

ISSN: 1471-2407