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Table 1 Distribution of HPV16 (sub)lineages according to cervical disease status (n = 194)

From: Association of cervical carcinogenesis risk with HPV16 E6 and E7 variants in the Taizhou area, China

Ages

NILM

CIN1

CIN2

CIN3

SCC

Total

42.2 ± 9.8

42.7 ± 8.5

39.6 ± 9.9

43.6 ± 6.7

55.3 ± 11.7

A1

4

2

1

2

1

10

A2

8

3

5

5

2

23

A3

5

5

3

6

0

19

A4*

40

11

19

45

10

125

A5

7

0

1

2

2

12

non-A

1

1

2

1

0

5

Total

65

22

31

61

15

194

  1. NILM negative for intraepithelial lesion or malignancy, CIN cervical intraepithelial neoplasia, SCC squamous cell carcinoma
  2. *The A4 (Asian) variants had a higher risk of CIN2+ than the A1–3 (European) variants when compared to CIN1 (OR = 2.69, 95% CI = 1.04 to 6.97, P < 0.05)