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Fig. 3 | BMC Cancer

Fig. 3

From: Prospective correlation between the patient microbiome with response to and development of immune-mediated adverse effects to immunotherapy in lung cancer

Fig. 3

Baseline microbiome composition. Bar and heatmap plots comparing baseline gut, nasal and buccal microbiomes in LC compared to HC. (a) Left: Bar graph showing relative ratios of phyla constitution in LC and HC samples. Right: Box plot showing a statistically significant decrease in α-diversity when comparing LC to HC patients (p = 9.36 × 10− 04). (b) Left: 2-dimensional PLS-DA graph identifying notable differences in genus expression when comparing LC vs HC samples. Right: Heatmap showing genus level expression in LC patients (upper half) compared with HC (lower half). There is a notable difference at the genus level. (c) Principal coordinate analysis (PCoA) comparing the beta-diversity of buccal, nasal and gut microbiome in LC patients

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BMC Cancer

ISSN: 1471-2407

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