Table 4 KEGG pathway analysis of DEGs associated with ccRCC
Term | Count | P Value | Genes |
|---|---|---|---|
hsa04966:Collecting duct acid secretion | 6 | 1.77E-05 | CLCNKB, SLC4A1, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2 |
hsa05150:Staphylococcus aureus infection | 7 | 5.12E-05 | C1QA, C1QB, C3, ITGB2, FCGR3A, FCGR3B, PLG |
hsa04145:Phagosome | 10 | 9.64E-05 | C3, TLR2, ITGB2, CTSS, ATP6V1G3, FCGR3A, ATP6V1B1, ATP6V0A4, FCGR3B, ATP6V0D2 |
hsa05323:Rheumatoid arthritis | 7 | 7.65E-04 | TNFSF13B, TLR2, ITGB2, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2 |
hsa05152:Tuberculosis | 9 | 0.001573 | C3, TLR2, FCER1G, ITGB2, CTSS, FCGR3A, ATP6V0A4, FCGR3B, ATP6V0D2 |
hsa04610:Complement and coagulation cascades | 6 | 0.001629 | KNG1, C1QA, C1QB, C3, SERPINA5, PLG |
hsa01100:Metabolic pathways | 26 | 0.006292 | ACOX2, TYRP1, ENPP3, HK2, UPP2, ATP6V1B1, LPCAT1, ENO2, ALDH4A1, ATP6V0D2, HPD, ALDH6A1, NDUFA4L2, SUCLG1, FBP1, PFKP, PCK2, MAN1C1, GGT6, RRM2, ABAT, ATP6V1G3, ATP6V0A4, DCXR, ACAA1, NNMT |
hsa03320:PPAR signaling pathway | 5 | 0.009598 | ACOX2, FABP1, PCK2, ACAA1, ANGPTL4 |
hsa00010:Glycolysis / Gluconeogenesis | 5 | 0.009598 | ENO2, FBP1, PFKP, HK2, PCK2 |
hsa05140:Leishmaniasis | 5 | 0.011719 | C3, TLR2, ITGB2, FCGR3A, FCGR3B |
hsa01200:Carbon metabolism | 6 | 0.013278 | ALDH6A1, SUCLG1, ENO2, FBP1, PFKP, HK2 |
hsa05133:Pertussis | 5 | 0.01412 | C1QA, C1QB, C3, ITGB2, CASP1 |
hsa05110:Vibrio cholerae infection | 4 | 0.026859 | ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2 |
hsa05134:Legionellosis | 4 | 0.029616 | C3, TLR2, ITGB2, CASP1 |
hsa04721:Synaptic vesicle cycle | 4 | 0.043794 | ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2 |
hsa05230:Central carbon metabolism in cancer | 4 | 0.045546 | SLC16A3, PDK1, PFKP, HK2 |
hsa00640:Propanoate metabolism | 3 | 0.047335 | ALDH6A1, SUCLG1, ABAT |
hsa01130:Biosynthesis of antibiotics | 7 | 0.04889 | SUCLG1, ENO2, FBP1, PFKP, HK2, PCK2, ACAA1 |
hsa05120:Epithelial cell signaling in Helicobacter pylori infection | 4 | 0.051005 | ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2 |
hsa00051:Fructose and mannose metabolism | 3 | 0.060164 | FBP1, PFKP, HK2 |
hsa04650:Natural killer cell mediated cytotoxicity | 5 | 0.065949 | FCER1G, ITGB2, FCGR3A, FCGR3B, TYROBP |
hsa00190:Oxidative phosphorylation | 5 | 0.084557 | NDUFA4L2, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2 |
hsa04960:Aldosterone-regulated sodium reabsorption | 3 | 0.085035 | FXYD4, HSD11B2, KCNJ1 |
hsa05322:Systemic lupus erythematosus | 5 | 0.086365 | C1QA, C1QB, C3, FCGR3A, FCGR3B |