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Table 5 OS analysis for patients with rectal cancer

From: The platelet to lymphocyte ratio is a potential inflammatory marker predicting the effects of adjuvant chemotherapy in patients with stage II colorectal cancer

Characteristics

 

RMSTb (95%CI)

HRc (95%CI)

P valuea

Interaction p

Non-chemotherapy

Chemotherapy

Total

–

53.7 (51.9–55.2)

56.2 (55.2–57.0)

0.539 (0.323–0.900)

0.016

–

Sex

Male

53.2 (50.7–55.1)

55.9 (54.4–57.0)

0.548 (0.298–1.006)

0.048

0.931

Female

54.5 (51.7–56.4)

56.8 (54.8–58.0)

0.534 (0.205–1.391)

0.192

 

Age (years)

≤55

54.3 (48.0–57.6)

56.3 (53.8–57.8)

1.204 (0.264–5.499)

0.810

0.314

56–60

55.4 (47.4–58.5)

56.8 (54.4–58.2)

0.698 (0.141–3.459)

0.658

 

61–65

53.3 (46.5–56.9)

55.7 (52.9–57.5)

0.490 (0.142–1.694)

0.250

 

66–70

53.2 (48.1–56.4)

57.3 (53.6–58.8)

0.605 (0.143–2.551)

0.489

 

> 70

53.6 (50.9–55.7)

54.6 (49.5–57.1)

0.568 (0.190–1.701)

0.305

 

Size (cm)

≤5.0

54.0 (51.2–55.8)

56.1 (54.5–57.2)

0.510 (0.260–1.002)

0.046

0.627

> 5.0

53.7 (50.5–55.8)

56.3 (54.5–57.5)

0.631 (0.280–1.422)

0.261

 

Differentiation

Well-moderate

53.9 (52.0–55.4)

56.3 (55.2–57.2)

0.519 (0.305–0.883)

0.014

0.309

Poor

52.0 (43.2–56.6)

54.7 (46.8–57.8)

0.727 (0.102–5.208)

0.750

 

T category

3

56.4 (53.7–58.0)

57.6 (55.5–58.6)

0.698 (0.253–1.925)

0.484

0.350

4

51.8 (49.2–54.0)

55.6 (54.2–56.8)

0.431 (0.237–0.784)

0.004

 

CEAd (ng/mL)

< 5

54.6 (51.9–56.4)

56.7 (55.3–57.8)

0.568 (0.273–1.181)

0.124

0.523

≥5

53.5 (50.1–55.7)

55.1 (52.8–56.8)

0.660 (0.273–1.598)

0.354

 

Examined lymph nodes

< 12

52.0 (47.5–54.9)

53.6 (50.2–55.6)

0.885 (0.375–2.091)

0.780

0.169

≥12

54.5 (52.3–56.0)

57.1 (55.9–57.9)

0.401 (0.208–0.771)

0.005

 

PLRe

≤130

56.0 (53.6–57.6)

56.0 (54.3–57.2)

0.898 (0.435–1.854)

0.770

0.033

> 130

51.3 (47.8–53.7)

56.5 (54.8–57.7)

0.289 (0.131–0.638)

0.001

 
  1. a P value of the log-rank test
  2. b RMST: the restricted mean survival time
  3. c HR: Hazard Ratio, chemotherapy patients vs. non-chemotherapy patients
  4. d CEA: carcinoembryonic antigen
  5. e PLR: platelet to lymphocyte ratio