Table 3 OS analysis for all patients
Characteristics | Â | RMSTb (95%CI) | HRc (95%CI) | P valuea | Interaction p | |
|---|---|---|---|---|---|---|
Non-chemotherapy | Chemotherapy | |||||
Total | – | 53.7 (51.9–55.2) | 56.2 (55.2–57.0) | 0.580 (0.388–0.866) | 0.007 | – |
Sex | Male | 53.2 (50.7–55.1) | 55.9 (54.4–57.0) | 0.592 (0.360–0.971) | 0.035 | 0.751 |
Female | 54.5 (51.7–56.4) | 56.8 (54.8–58.0) | 0.560 (0.282–1.112) | 0.093 |  | |
Age (years) | ≤55 | 54.3 (48.0–57.6) | 56.3 (53.8–57.8) | 0.620 (0.225–1.708) | 0.350 | 0.844 |
56–60 | 55.4 (47.4–58.5) | 56.8 (54.4–58.2) | 0.725 (0.199–2.634) | 0.623 |  | |
61–65 | 53.3 (46.5–56.9) | 55.7 (52.9–57.5) | 0.636 (0.240–1.683) | 0.357 |  | |
66–70 | 53.2 (48.1–56.4) | 57.3 (53.6–58.8) | 0.355 (0.118–1.063) | 0.053 |  | |
> 70 | 53.6 (50.9–55.7) | 54.6 (49.5–57.1) | 0.834 (0.371–1.875) | 0.660 |  | |
Location | Rectum | 52.2 (49.2–54.5) | 55.6 (53.9–56.9) | 0.539 (0.323–0.900) | 0.016 | 0.479 |
Colon | 55.2 (52.8–56.9) | 56.9 (55.4–58.1) | 0.612 (0.321–1.168) | 0.132 |  | |
Size (cm) | ≤5.0 | 54.0 (51.2–55.8) | 56.1 (54.5–57.2) | 0.621 (0.361–1.067) | 0.081 | 0.255 |
> 5.0 | 53.7 (50.5–55.8) | 56.3 (54.5–57.5) | 0.561 (0.306–1.028) | 0.058 |  | |
Differentiation | Well-moderate | 53.9 (52.0–55.4) | 56.3 (55.2–57.2) | 0.569 (0.373–0.868) | 0.008 | 0.396 |
Poor | 52.0 (43.2–56.6) | 54.7 (46.8–57.8) | 0.662 (0.177–2.471) | 0.534 |  | |
T category | 3 | 56.4 (53.7–58.0) | 57.6 (55.5–58.6) | 0.654 (0.277–1.543) | 0.328 | 0.382 |
4 | 51.8 (49.2–54.0) | 55.6 (54.2–56.8) | 0.501 (0.318–0.791) | 0.002 |  | |
CEAd (ng/mL) | < 5 | 54.6 (51.9–56.4) | 56.7 (55.3–57.8) | 0.585 (0.323–1.060) | 0.073 | 0.482 |
≥5 | 53.5 (50.1–55.7) | 55.1 (52.8–56.8) | 0.734 (0.384–1.404) | 0.348 |  | |
Examined lymph nodes | < 12 | 52.0 (47.5–54.9) | 53.6 (50.2–55.6) | 0.793 (0.414–1.520) | 0.483 | 0.415 |
≥12 | 54.5 (52.3–56.0) | 57.1 (55.9–57.9) | 0.500 (0.300–0.835) | 0.007 |  | |
PLRe | ≤130 | 56.0 (53.6–57.6) | 56.0 (54.3–57.2) | 0.983 (0.528–1.829) | 0.956 | 0.027 |
> 130 | 51.3 (47.8–53.7) | 56.5 (54.8–57.7) | 0.371 (0.212–0.649) | < 0.001 |  | |