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Table 5 Statistically significant associations of KLRG1, BTK, CCR2 and SCML4 expressions with overall survival in LUAD patients

From: Functions and clinical significance of KLRG1 in the development of lung adenocarcinoma and immunotherapy

Outcome

OS

HR

95% CI

P value

KLRG1 expression level (high vs. low)

1.658

1.202–2.288

0.002

BTK expression level (high vs. low)

1.889

1.381–2.585

< 0.001

CCR2 expression level (high vs. low)

1.922

1.404–2.631

< 0.001

SCML4 expression level (high vs. low)

1.638

1.225–2.191

0.001

Diagnosis Age <  65 vs. ≥ 65

3.553

1.122–11.253

0.031

Neoplasm Disease Stage I, II vs. III, IV, V

1.788

1.391–2.298

< 0.001

Mutation Count

<  230 vs. ≥ 230

1.001

0.850–1.178

0.995

Gender

Female vs. Male

1.043

0.779–1.396

0.779

Smoking History Categorya

1 vs. 2, 3, 4, 5

0.966

0.681–1.371

0.847

  1. P values are derived from Cox regression analysis
  2. aSmoking history: 1: lifelong non-smoker; 2: current smoker; 3. Current reformed smoker (for> 15 years); 4. Current reformed smoker (for≤15 years); 5. Current reformed smoker (duration not specified)