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Fig. 7 | BMC Cancer

Fig. 7

From: miR-29a-3p inhibits endometrial cancer cell proliferation, migration and invasion by targeting VEGFA/CD C42/PAK1

Fig. 7

miR-29a-3p suppressed EC cells growth in vivo by inhibiting CDC42/PAK1 signaling pathway activity via targeting VEGFA. A VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on xenograft tumors volume in vivo. ** P < 0.01 relative to miR-29a-3p mimic group. *** P < 0.001 relative to miR-NC group. B VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on xenograft tumor weight in vivo. * P < 0.05 and ** P < 0.01. C VEGFA up-regulation reversed the inhibitory effect of miR-29a-3p on the expression of CDC42 and p-PAK1/PAK1 protein in xenograft tumors. * P < 0.05, ** P < 0.01 and *** P < 0.001

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BMC Cancer

ISSN: 1471-2407

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