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Table 4 Univariate and multivariate cox analysis for cancer-specific survival analysis

From: Prognostic nomogram for hepatocellular carcinoma with radiofrequency ablation: a retrospective cohort study

  

Univariate cox

Multivariate cox

 

HR

95%CI

P-value

HR

95%CI

P-value

Marital status

Married

Reference

   

Separated

1.25

1.07–1.47

0.006

1.25

1.06–1.47

0.009

Single

1.28

1.09–1.5

0.003

1.35

1.15–1.60

< 0.001

Age

< 65

Reference

   

65–75

1.15

0.99–1.33

0.072

1.26

1.08–1.47

0.004

> 75

1.79

1.47–2.19

< 0.001

1.98

1.61–2.43

< 0.001

Race

Other

Reference

   

White

1.75

1.47–2.08

< 0.001

1.75

1.46–2.09

< 0.001

Black

1.5

1.18–1.92

0.001

1.41

1.09–1.81

0.008

Sex

female

Reference

   

male

1.04

0.89–1.21

0.632

   

Histological grade

Well differentiated

Reference

   

Moderately differentiated

1.23

0.98–1.54

0.077

1.19

0.95–1.50

0.131

Poorly differentiated

1.55

1.11–2.18

0.01

1.49

1.06–2.10

0.023

Undifferentiated

4.19

1.33–13.18

0.014

2.54

0.80–8.10

0.115

unknown

1.16

0.96–1.41

0.128

1.25

1.03–1.52

0.024

T

T1a

Reference

   

T1b

1.54

1.22–1.94

< 0.001

1.08

0.83–1.39

0.574

T2

1.94

1.52–2.47

< 0.001

1.39

1.07–1.80

0.013

T3

3.83

2.73–5.37

< 0.001

1.63

1.11–2.39

0.013

T4

5.34

3.52–8.11

< 0.001

2.40

1.54–3.73

< 0.001

N

N0

Reference

   

N1

1.49

0.97–2.3

0.071

   

M

M0

Reference

   

M1

2.21

1.33–3.69

0.002

1.65

0.97–2.81

0.063

Radiation therapy

Unradiation

Reference

   

Radiation

1.64

1.13–2.38

0.009

1.03

0.70–1.52

0.865

Chemotherapy

Unchemotherapy

Reference

   

chemotherapy

1.1

0.96–1.26

0.168

   

Tumor size

0-28 mm

Reference

   

28-35 mm

1.31

1.09–1.56

0.003

1.33

1.10–1.60

0.004

> 35 mm

2.35

2.03–2.72

< 0.001

2.16

1.83–2.56

< 0.001

Afp

nomal-afp

Reference

   

up-afp

1.42

1.22–1.64

< 0.001

1.44

1.24–1.67

< 0.001

Fibersis

non-fibersis

Reference

   

fibersis

1.05

0.8–1.4

0.709

   

unknown

1.15

0.88–1.51

0.294

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