Table 4 Risk factors correlated with cancer-specific and overall survival in all appendiceal cancer patients diagnosed during 2012–2016

  ≤ 56

1

  > 56

1.63 (1.39–1.92)

<.0001

 Male

1

 Female

0.83 (0.71–0.96)

0.015

 Married

1

1

 Unmarried^a

1.24 (1.02–1.5)

0.03

1.24 (1.06–1.45)

0.0065

 Unknown

1.09 (0.66–1.8)

0.7293

1.18 (0.82–1.71)

0.3771

 West

1

 South

1.37 (1.14–1.64)

0.0006

 Midwest

1.25 (0.97–1.61)

0.0847

 Northwest

1.19 (0.96–1.47)

0.1055

 Negative

1

1

 Positive

1.49 (1.13–1.96)

0.0052

1.3 (1.02–1.64)

0.0316

 Unknown

0.91 (0.71–1.19)

0.4996

0.95 (0.77–1.18)

0.6546

 Negative

1

1

 Positive

1.45 (1.11–1.9)

0.0064

1.53 (1.22–1.91)

0.0002

 Unknown

1.44 (1.15–1.8)

0.0013

1.23 (1.02–1.48)

0.027

 Harvested lymph nodes

1

  ≤ 12

0.56 (0.46–0.69)

<.0001

  > 12

1.12 (0.49–2.57)

0.7879

 Unknown

 GCC

1

1

 MAC

1.8 (1.17–2.78)

0.0075

1.6 (1.16–2.22)

0.0046

 NMAC

2.76 (1.81–4.21)

<.0001

2.56 (1.86–3.5)

<.0001

 SRCC

2.21 (1.39–3.52)

0.0009

2.18 (1.53–3.12)

<.0001

 MiNENs

2.19 (1.32–3.66)

0.0026

1.67 (1.11–2.52)

0.0136

 NECs

0.54 (0.19–1.5)

0.235

0.99 (0.54–1.81)

0.9704

 NETs

0.3 (0.12–0.73)

0.0086

0.89 (0.54–1.46)

0.6515

 T1

1

1

 T2

0.73 (0.34–1.57)

0.4247

0.95 (0.6–1.49)

0.8078

 T3

1.14 (0.65–1.99)

0.642

1.21 (0.83–1.77)

0.322

 T4

1.71 (1–2.94)

0.0516

1.73 (1.19–2.51)

0.0042

 N0

1

1

 N1

2.46 (1.91–3.17)

<.0001

0.56 (0.48–0.66)

<.0001

 N2

3.73 (2.84–4.9)

<.0001

1.18 (0.62–2.24)

0.6124

 M0

1

1

 M1

2.54 (1.98–3.26)

<.0001

2.15 (1.76–2.62)

<.0001

 Well differentiated

1

1

 Moderately differentiated

2.38 (1.66–3.42)

<.0001

1.84 (1.44–2.36)

<.0001

 Poorly or un-differentiated

3.4 (2.32–4.97)

<.0001

2.46 (1.88–3.23)

<.0001

 Unknown

3.2 (2.18–4.71)

<.0001

2.42 (1.85–3.15)

<.0001

 No

1

1

 Yes

0.72 (0.58–0.91)

0.0051

0.59 (0.49–0.71)

<.0001