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Fig. 4 | BMC Cancer

Fig. 4

From: Development of a liquid biopsy based purely quantitative digital droplet PCR assay for detection of MLH1 promoter methylation in colorectal cancer patients

Fig. 4

Distribution of detected positive droplets for MLH1 methylation in Normal and CRC Samples. With 1 ng input cfDNA, 20 normal and 28 CRC samples were treated or untreated with HpaII enzyme. In both populations the untreated samples showed higher positive droplets than the treated samples. Compared to normal samples, significant higher methylation levels in the cancer population (P < 0.001)

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BMC Cancer

ISSN: 1471-2407

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