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Table 2 Clinical features of primary mammary tumours collected from Mmtv-Pymt mice that met the inclusion criteria for the study. Mammary tumours were collected from Mmtv-Pymt transgenic mice at either estrus or diestrus phase of the ovarian cycle. Ovarian cycle stage was determined by cytological analysis of vaginal smears, performed for at least 2 weeks. All tumours are estrogen receptor positive as determined through immunohistochemistry. No differences in tumour features were observed between ovarian cycle stages

From: Ovarian cycle stage critically affects 21-gene recurrence scores in Mmtv-Pymt mouse mammary tumours

Characteristics

Estrus n (%)

Diestrus n (%)

Total Number

25

28

Mouse age (Days; range)

78 (50 - 101)

75 (43 - 96)

Mouse Body Weight (Grams; range)

23.5 (17.0 – 27.4)

24.3 (19.3 – 30.8)

Tumour Latency (Days; range)

54.2 (20 - 89)

47.0 (33 - 85)

Tumour Size

 <10mm

6 (24)

6 (21)

 10 – 15mm

9 (36)

10 (36)

 16 – 20mm

8 (32)

7 (25)

 >20mm

2 (8)

5 (18)

Tumour Weight (Milligrams; range)

469.8 (95.1 – 953.9)

449.6 (93.7 – 1366.3)

Tumour Grade

 2

4 (16)

2 (7)

 3

7 (28)

7 (25)

 4

14 (56)

19 (68)