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Table 3 Multivariate logistic regression analysis of the training dataset

From: The incidence, risk factors and predictive nomograms for early death of lung cancer with synchronous brain metastasis: a retrospective study in the SEER database

Variable

Overall early-death

Cancer-specific early-death

 

OR

95% CI

P

OR

95% CI

P

Gender

 Male

Ref

  

Ref

  

 Female

0.742

0.703–0.783

< 0.001

0.773

0.731–0.817

< 0.001

Age

  < 40

Ref

  

Ref

  

 40–49

1.715

1.133–2.596

0.011

1.558

1.011–2.4

0.044

 50–59

2.634

1.769–3.923

< 0.001

2.377

1.57–3.597

< 0.001

 60–69

3.494

2.35–5.197

< 0.001

3.144

2.08–4.51

< 0.001

 70–79

5.296

3.559–7.881

< 0.001

4.634

3.065–7.007

< 0.001

  > =80

7.726

5.162–11.563

< 0.001

6.176

4.062–9.389

< 0.001

Race

 White

Ref

  

Ref

  

 Black

0.941

0.867–1.022

0.151

0.923

0.847–1.005

0.064

 Other

0.728

0.657–0.806

< 0.001

0.733

0.659–0.816

< 0.001

Histology

 AD

Ref

  

Ref

  

 SQCC

1.555

1.425–1.697

< 0.001

1.477

1.351–1.614

< 0.001

 LCLC

1.188

0.994–1.42

0.058

1.178

0.981–1.415

0.08

 SCLC

0.975

0.901–1.056

0.541

0.96

0.885–1.043

0.336

 Other

1.434

1.336–1.539

< 0.001

1.315

1.223–1.414

< 0.001

Gleason grade

 I

Ref

  

Ref

  

 II

1.106

0.865–1.413

0.423

1.146

0.887–1.482

0.297

 III

1.669

1.322–2.108

< 0.001

1.673

1.31–2.136

< 0.001

 IV

1.555

1.187–2.038

< 0.001

1.614

1.218–2.137

0.001

 Unknown

1.446

1.148–1.800

0.002

1.412

1.109–1.799

0.005

T Stage

 T0

Ref

  

Ref

  

 T1

0.951

0.71–1.273

0.734

1.334

0.951–1.872

0.095

 T2

1.221

0.919–1.624

0.169

1.787

1.283–2.489

0.001

 T3

1.512

1.137–2.01

0.004

2.138

1.535–2.978

< 0.001

 T4

1.662

1.252–2.208

< 0.001

2.389

1.717–3.323

< 0.001

 Tx

1.675

1.255–2.236

< 0.001

2.247

1.608–3.141

< 0.001

N Stage

 N0

Ref

  

Ref

  

 N1

0.877

0.786–0.979

0.019

0.904

0.806–1.013

0.082

 N2

1.13

1.053–1.212

0.001

1.146

1.065–1.232

< 0.001

 N3

1.108

1.018–1.207

0.018

1.145

1.048–1.25

0.003

 Nx

1.257

1.107–1.426

< 0.001

1.212

1.065–2.38

0.004

Bone Met

 Yes

Ref

  

Ref

  

 None

0.791

0.746–0.839

< 0.001

0.795

0.748–0.844

< 0.001

 Unknown

0.82

0.665–1.011

0.063

0.742

0.597–0.921

0.007

Liver Met

 Yes

Ref

  

Ref

  

 None

0.566

0.529–0.605

< 0.001

0.594

0.555–0.635

< 0.001

 Unknown

0.734

0.607–0.887

0.001

0.816

0.672–0.989

0.039

Marital

 Single

Ref

  

Ref

  

 Married

0.757

0.717–0.8

< 0.001

0.779

0.736–0.824

< 0.001

 Unknown

0.897

0.781–1.03

0.122

0.836

0.723–0.965

0.015