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Table 5 Acute and late toxicities after high-precision radiotherapy of liver metastases

From: Analysis of using high-precision radiotherapy in the treatment of liver metastases regarding toxicity and survival

Acute toxicity (n = 115) Grade 1
absolute/ (%)
Grade 2
absolute/ (%)
Grade 3
absolute/ (%)
Nausea 20 (17.4) 8 (7.0) 0 (0.0)
Vomiting 7 (6.1) 5 (4.3) 0 (0.0)
Abdominal pain 17 (14.8) 2 (1.7) 0 (0.0)
Loss of weight 3 (2.6) 1 (0.9) 0 (0.0)
Loss of appetite 9 (7.8) 0 (0.0) 0 (0.0)
Diarrhea 7 (6.1) 2 (1.7) 0 (0.0)
Constipation 15 (13.0) 1 (0.9) 0 (0.0)
Flatulence 3 (2.6) 0 (0.0) 0 (0.0)
Dyspepsia/Reflux 4 (3.5) 0 (0.0) 0 (0.0)
Swallowing difficulties 2 (1.7) 0 (0.0) 0 (0.0)
Rad. liver-parenchymal abnormalities 2 (1.7) 0 (0.0) 0 (0.0)
Radiogenic hepatitis 0 (0.0) 2 (1.7) 0 (0.0)
Cholestasis/biliary stenosis 1 (0.9) 1 (0.9) 0 (0.0)
Subileus/Corpostasis 0 (0.0) 0 (0.0) 1 (0.9)
Esophagusstenosis 0 (0.0 0 (0.0) 1 (0.9)
Fatigue 38 (33.0) 13 (11.3) 0 (0.0)
Erythema/Radiodermatitis 1 (0.9) 1 (0.9) 0 (0.0)
Thoracic−/ribpain 0 (0.0) 1 (0.9) 0 (0.0)
Fever/chills/sweating 6 (5.2) 2 (1.7) 0 (0.0)
Hyperpigmentation/scarring 1 (0.9) 0 (0.0) 0 (0.0)
Dizziness 1 (0.9) 0 (0.0) 0 (0.0)
Rad. pneumonitis 0 (0.0) 2 (1.7) 0 (0.0)
Late toxicity (n = 115) Grade 1
absolute/ (%)
Grade 2
absolute/ (%)
Grade 3
absolute/ (%)
Nausea 4 (3.5) 2 (1.7) 0 (0.0)
Vomiting 2 (1.7) 2 (1.7) 0 (0.0)
Abdominal pain 13 (11.3) 8 (7.0) 2 (1.7)
Loss of weight 4 (3.5) 3 (2.6) 0 (0.0)
Loss of appetite 5 (4.3) 2 (1.7) 0 (0.0)
Diarrhea 6 (5.2) 1 (0.9) 0 (0.0)
Constipation 3 (2.6) 3 (2.6) 0 (0.0)
Flatulence 2 (1.7) 1 (0.9) 0 (0.0)
Dyspepsia/Reflux 1 (0.9) 0 (0.0) 0 (0.0)
Cholestasis/biliary stenosis 4 (3.5) 1 (0.9) 4 (3.5)
Rad. liver-parenchymal abnormalities 0 (0.0) 2 (1.7) 0 (0.0)
Cholangitis 0 (0.0) 1 (0.9) 2 (1.7)
Liver failure/encephalopathy 0 (0.0) 0 (0.0) 1 (0.9)
Liverabscess 0 (0.0) 0 (0.0) 1 (0.9)
Fatigue 8 (7.0) 9 (7.8) 0 (0.0)
Erythema/Radiodermatitis 1 (0.9) 0 (0.0) 0 (0.0)
Thoracic−/ribpain 1 (0.9) 2 (1.7) 0 (0.0)
Rad. lung abnormalities 2 (1.7) 0 (0.0) 0 (0.0)
Hyperpigmentation/scarring 2 (1.7) 1 (0.9) 0 (0.0)
Dry cough 1 (0.9) 1 (0.9) 0 (0.0)
Numbness in the irradiation field 0 (0.0) 1 (0.9) 0 (0.0)