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Table 6 Gene sets enriched in the low risk phenotype via GO

From: A novel immune-related gene pair prognostic signature for predicting overall survival in bladder cancer

Gene set name NES NOM p-val FDR q-val
GO_T_CELL_CYTOKINE_PRODUCTION −1.594 0.034 0.227
GO_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE −1.721 0.036 0.195
GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE −1.740 0.034 0.192
GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION −1.747 0.028 0.188
GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_LINEAGE_COMMITMENT −1.754 0.019 0.183
GO_CD8_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION − 1.798 0.019 0.160
GO_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE −1.807 0.024 0.161
GO_POSITIVE_REGULATION_OF_PROTEIN_DEACETYLATION −1.836 0.006 0.146
GO_POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR −1.838 0.004 0.149
GO_MHC_PROTEIN_COMPLEX −1.838 0.002 0.150
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION −1.859 0.006 0.146
GO_FATTY_ACID_BETA_OXIDATION −1.872 0.004 0.147
GO_T_CELL_SELECTION −1.889 0.017 0.156
GO_IMMUNOGLOBULIN_PRODUCTION −1.898 0.002 0.163
GO_CD4_POSITIVE_OR_CD8_POSITIVE_ALPHA_BETA_T_CELL_LINEAGE_COMMITMENT −1.919 0.004 0.157
GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY −1.920 0.008 0.161
GO_FATTY_ACID_CATABOLIC_PROCESS −1.936 0.004 0.168
GO_POSITIVE_T_CELL_SELECTION −1.944 0.004 0.194
GO_T_CELL_RECEPTOR_COMPLEX −1.972 0.002 0.260
GO_MHC_PROTEIN_BINDING −1.994 0.006 0.369
  1. Gene sets with NOM p-val < 0.05 and FDR q-val < 0.25 were considered significant
  2. GO Gene Ontology, NES normalized enrichment score, NOM nominal, FDR false discovery rate