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Table 5 Gene sets enriched in the high risk phenotype via GO

From: A novel immune-related gene pair prognostic signature for predicting overall survival in bladder cancer

Gene set name NES NOM p-val FDR q-val
GO_CHONDROCYTE_DIFFERENTIATION 2.459 < 0.001 < 0.001
GO_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT 2.444 < 0.001 < 0.001
GO_CHONDROCYTE_DEVELOPMENT 2.400 < 0.001 < 0.001
GO_COLLAGEN_CONTAINING_EXTRACELLULAR_MATRIX 2.389 < 0.001 < 0.001
GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION 2.301 < 0.001 0.001
GO_EXTRACELLULAR_MATRIX_COMPONENT 2.264 < 0.001 0.002
GO_COLLAGEN_FIBRIL_ORGANIZATION 2.253 < 0.001 0.002
GO_COLLAGEN_BINDING 2.250 < 0.001 0.002
GO_COLLAGEN_TRIMER 2.241 0.002 0.003
GO_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT_CONFERRING_TENSILE_STRENGTH 2.222 < 0.001 0.003
GO_POSITIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION 2.219 < 0.001 0.003
GO_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION 2.175 < 0.001 0.005
GO_EXTRACELLULAR_MATRIX_BINDING 2.105 < 0.001 0.011
GO_POSITIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION 2.042 < 0.001 0.018
GO_ENDOTHELIAL_CELL_PROLIFERATION 1.990 0.002 0.024
GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION 1.942 0.002 0.031
GO_ENDOTHELIAL_CELL_MIGRATION 1.881 0.006 0.040
GO_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION 1.833 0.006 0.049
GO_FIBROBLAST_PROLIFERATION 1.801 0.006 0.056
GO_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION 1.770 0.011 0.063
  1. Gene sets with NOM p-val < 0.05 and FDR q-val < 0.25 were considered significant
  2. GO Gene Ontology, NES normalized enrichment score, NOM nominal, FDR false discovery rate