Fig. 3

Characteristics of the IRGP signature using the TCGA. The score of included IRGPs in different groups (A). The categorization of BC patients into different groups (B). The survival status of patients in the high-risk group and low-risk group (C). Through ROC curve analysis, the cutoff value for dividing BC patients into the high-risk group and the low-risk group was determined to be 0.538 (D). The AUC of the ROC curve results showed a moderate prognostic power of the risk score (E). The results of Kaplan-Meier survival analysis revealed that a high-risk score was significantly related to poor OS (F). Univariate and multivariate Cox regression analyses demonstrated that the risk score was an independent prognostic factor (G-H). TCGA, The Cancer Genome Atlas; LASSO, least absolute shrinkage and selection operator; BLCA, bladder cancer; BC, bladder cancer; IRGPs, immune-related gene pairs; AUC, area under curve; ROC, receiver operating characteristic; OS, overall survival