Table 3 Univariate and multivariate analyses for recurrence of hepatocellular carcinoma
Factors | No. Patients | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | ||
Sex | |||||
Male | 169 (79.7%) | 0.850 (0.509 - 1.419) | 0.533 | ||
Female | 43 (20.3%) | ||||
HBV DNA level preoperation | |||||
< 2000 IU/mL | 104 (49.1%) | 1.629 (1.095 - 2.423) | 0.016 | 1.007 (0.653 - 1.553) | 0.976 |
≥ 2000 IU/mL | 108 (50.9%) | ||||
Cirrhosis | |||||
Yes | 167 (78.8%) | 0.812 (0.513 - 1.286) | 0.375 | ||
No | 45 (21.2%) | ||||
Tumor diameter | |||||
< 5cm | 110 (51.9%) | 1.934 (1.300 - 2.877) | 0.001 | 1.819 (1.193 - 2.775) | 0.005 |
≥ 5cm | 102 (48.1%) | ||||
Capsule formation | |||||
Yes | 130 (61.3%) | 0.850 (0.573 - 1.261) | 0.42 | ||
No | 82 (38.7%) | ||||
Metastasis in the liver | |||||
Yes | 24 (11.3%) | 2.077 (1.196 - 3.607) | 0.009 | 1.916 (1.077 - 3.407) | 0.027 |
No | 188 (88.7%) | ||||
AFP preoperation | |||||
< 10 ng/mL | 65 (30.7%) | 1.714 (1.089 - 2.698) | 0.02 | 1.462 (0.919 - 2.324) | 0.109 |
≥ 10 ng/mL | 147 (69.3%) | ||||
HBsAg | |||||
< 250 IU/mL | 45 (21.2%) | 1.042 (0.644 - 1.686) | 0.867 | ||
≥ 250 IU/mL | 167 (78.8%) | ||||
HBeAg | |||||
Positive | 61 (28.8%) | 1.162 (0.765 - 1.764) | 0.481 | ||
Negative | 151 (71.2%) | ||||
HBV DNA level at follow-up | |||||
< 100 IU/mL | 128 (60.4%) | 2.725 (1.836 - 4.044) | < 0.000 | 2.943 (1.916 - 4.520) | < 0.000 |
≥ 100 IU/mL | 84 (39.6%) | ||||