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Table 3 Predictive value (PPV), Sensitivity, AUC (area under the curve) and their 95% confidence intervals (CI) of all cancer patients and by cancer types, using the Swedish Cancer Register as ‘gold standard’ reference

From: Diagnostic codes of cancer in Skåne healthcare register: a validation study using individual-level data in southern Sweden

 

Cancer Register

Skåne Healthcare Register

Number of cancer patientsa

Number of cancer patientsa

PPV (95%CI), %

Sensitivity (95%CI), %

AUC (95%CI)

All cancers

61,693

87,650

63.76 (63.44–64.08)

90.58 (90.35–90.81)

0.94 (0.94–0.94)

Cancers of lip, oral cavity and pharynx

1142

1298

72.85 (70.21–75.38)

74.96 (72.34–77.45)

0.87 (0.86–0.89)

Cancers of digestive organs

10,549

11,877

80.13 (79.38–80.86)

85.99 (85.31–86.65)

0.93 (0.93–0.93)

 Esophagus

523

465

89.03 (85.83–91.72)

79.16 (75.42–82.56)

0.90 (0.88–0.91)

 Colorectal

6837

6774

88.22 (87.43–88.98)

87.41 (86.60–88.18)

0.94 (0.93–0.94)

 Liver

902

1059

55.43 (52.38–58.45)

65.08 (61.87–68.19)

0.83 (0.81–0.84)

 Pancreas

930

1432

53.49 (50.87–56.10)

82.37 (79.76–84.76)

0.91 (0.90–0.92)

Cancers of lung and thorax

5244

5381

84.64 (83.61–85.63)

80.68 (79.59–81.74)

0.90 (0.90–0.91)

 Bronchus and lung

4916

4502

86.34 (85.30–87.33)

79.07 (77.90–80.20)

0.90 (0.89–0.90)

Bone cancer

95

240

43.40 (35.57–51.48)

72.63 (62.52–81.28)

0.86 (0.82–0.91)

Skin cancer

7434

29,371

20.08 (19.60–20.56)

73.94 (72.93–74.94)

0.86 (0.86–0.87)

 Melanoma skin cancer

3104

3267

74.64 (73.07–76.16)

74.81 (73.24–76.33)

0.87 (0.87–0.88)

 Non-melanoma skin cancer

4330

26,104

11.50 (11.09–11.91)

63.28 (61.82–64.72)

0.81 (0.80–0.82)

Cancers of soft tissues

361

797

52.74 (47.73–57.71)

58.73 (53.45–63.85)

0.79 (0.77–0.82)

Breast cancer

8681

9451

87.31 (86.62–87.98)

93.74 (93.21–94.25)

0.97 (0.97–0.97)

Other female genital cancers

3029

3476

81.70 (80.34–83.01)

88.61 (87.42–89.72)

0.94 (0.94–0.95)

 Uterus

1293

1166

92.28 (90.60–93.75)

83.22 (81.07–85.22)

0.92 (0.91–0.93)

Male genital cancers

11,318

11,356

89.43 (88.84–90.00)

88.06 (87.45–88.66)

0.94 (0.94–0.94)

 Prostate

10,748

10,421

90.53 (89.95–91.08)

87.77 (87.14–88.39)

0.94 (0.94–0.94)

Cancers of urinary tract

4526

4937

83.65 (82.57–84.70)

87.41 (86.40–88.36)

0.94 (0.93–0.94)

 Kidney

1224

1402

74.04 (71.66–76.32)

84.80 (82.67–86.77)

0.92 (0.91–0.93)

 Bladder

3302

3219

87.57 (86.38–88.69)

85.37 (84.12–86.56)

0.93 (0.92–0.93)

Cancers of central nervous system and eye

1712

1452

66.81 (64.24–69.31)

53.15 (50.76–55.54)

0.77 (0.75–0.78)

Cancers of endocrine glands

1647

671

73.19 (69.53–76.64)

27.69 (25.54–29.92)

0.64 (0.63–0.65)

Hematologic malignancies

4117

4779

75.45 (74.17–76.69)

84.11 (82.96–85.22)

0.92 (0.91–0.93)

Others

1838

2564

41.69 (39.04–44.38)

30.58 (28.48–32.74)

0.65 (0.64–0.66)

  1. a If multiple records, we counted the first primary diagnosis of cancer for each patient