Fig. 1
From: Clinicopathologic features of TDO2 overexpression in renal cell carcinoma
TDO2 expression and association with progression and prognosis. a, b TDO2 expression in TCGA RCC. a TDO2 expression in normal and tumor tissues. b TDO2 expression associated with clinicopathologic features; Kaplan-Meier analysis of RCC patients with high and low TDO2 expression. Unit: log2(count+ 1), Wilcox/Kruskal-Wallis test. c Validating TDO2 expression in 12 pairs of normal and tumor tissue samples by qRT-PCR. The data are displayed as mean ± SD (n = 3). d Immunohistochemical staining of TDO2 in a RCC sample, original magnification × 40. Normal kidney showed weak cytoplasmic staining (upper right corner, original magnification × 400), whereas tumor cells showed strong cytoplasmic staining with TDO2 (lower right corner, original magnification × 400). (e) Survival analysis of RCC patients with high and low TDO2 expression by Kaplan-Meier method