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Table 3 Dose constraints of normal tissue. The biologically effective dose in 2 Gy fractions (BED2Gy) is calculated assuming an alpha/beta value of 2Gy for all normal tissues. ALARA As low as reasonable achievable. Dose constraints of can be exceeded in case of tumor involvement and with agreement of the patient

From: Adenoid cystic Carcinoma and Carbon ion Only irradiation (ACCO): Study protocol for a prospective, open, randomized, two-armed, phase II study

Organ at risk

Dose contraints

BED2Gy

 

Brain stem

54Gy(RBE)/82%

60Gy

Dmax superficial

Chiasma

49.5Gy(RBE)/75%

52.6Gy

Dmax

Optic nerves

49.5Gy(RBE)/75%

52.6Gy

Dmax

Spinal cord

45Gy(RBE)/68%

45.3Gy

Dmax

Parotid gland

31Gy(RBE)/47%

26.4Gy

Dmean

Lower jaw

60Gy(RBE)/90%

69.8Gy

Dmax superficial

Lens

ALARA

  

Bulb

ALARA

  

Lacrimal gland

ALARA

  

Inner ear

ALARA

  

Temporomandibular joint

ALARA