Table 4 Incidence of adverse reactions
Variable | Patients (N = 39) | |
|---|---|---|
Any grade, N (%) | Grade 3 or 4, N (%) | |
Leukopenia | 27 (73.0) | 0 (0) |
Granulocytopenia | 29 (78.4) | 0 (0) |
Thrombocytopenia | 6 (16.2) | 1 (2.7) |
Elevated transaminase | 9 (24.3) | 0 (0) |
Hand-foot syndrome | 9 (24.3) | 0 (0) |
Stomatitis | 14 (37.8) | 0 (0) |
Fatigue | 20 (54.1) | 0 (0) |
Proteinuria | 4 (10.8) | 0 (0) |
Gastrointestinal hemorrhage | 2 (5.4) | 1 (2.7) |
Hypertension | 10 (27.0) | 1 (2.7) |
Neurotoxicity | 10 (27.0) | 0 (0) |
Gastrointestinal perforation | 1 (2.7) | 1 (2.7) |