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Fig. 3 | BMC Cancer

Fig. 3

From: Evaluation of body-surface-area adjusted dosing of high-dose methotrexate by population pharmacokinetics in a large cohort of cancer patients

Fig. 3

Probability of target attainment (PTA) across body surface area (BSA) groups under BSA-based, flat and stratified dosing regimens. Reference BSA-based dose levels range from 500 to 2000 mg/m2. Numbers in the bars represent respective PTA values. (0 = < 25%, 1 = 25–50%, 2 = 50–75%, 3 = > 75%). Description of doses under each regimen is presented in Table 4

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