Variables | No. of studies | x2 for heterogeneity | Model selected | OR a (95% CI b) | P for OR heterogeneity |
---|---|---|---|---|---|
Total | 48 | 1249.27 | Random | 0.90 (0.86, 0.95) | < .001 |
Hormones resource | Â | Â | Â | Â | .190 |
 Endogenesis | 26 | 679.81 | Random | 0.92 (0.87, 0.98) | < .001 |
 Exogenesis | 36 | 419.73 | Random | 0.86 (0.80, 0.93) | < .001 |
Study design | Â | Â | Â | Â | .950 |
 Retrospective | 34 | 573.55 | Random | 0.90 (0.85, 0.96) | < .001 |
 Prospective | 14 | 667.58 | Random | 0.90 (0.81, 1.00) | < .001 |
Publication date | Â | Â | Â | Â | .370 |
 1987–2007 | 22 | 232.66 | Random | 0.88 (0.82, 0.94) | < .001 |
 2008–2019 | 26 | 1016.31 | Random | 0.92 (0.86, 0.99) | < .001 |