Table 2 Alcohol’s effects on CVD, IHD, and stroke risks among male long-term survivors of colorectal cancer
Outcome | 0 g/day (n = 6888) | 0.1–9.9 g/day (n = 1903) | 10–19.9 g/day (n = 1064) | 20–29.9 g/day (n = 781) | 30–39.9 g/day (n = 350) | ≥ 40 g/day (n = 788) | P for trend |
|---|---|---|---|---|---|---|---|
CVD | 0.148 | ||||||
Event (%) | 369 (5.4) | 92 (4.8) | 47 (4.4) | 43 (5.5) | 21 (6.0) | 59 (7.5) | |
Person-years | 22,818 | 6295 | 3525 | 2441 | 1120 | 2688 | |
HR (95% CI) | 1.00 (Reference) | 1.00 (0.80–1.27) | 0.89 (0.65–1.21) | 1.25 (0.90–1.73) | 1.16 (0.74–1.82) | 1.40 (1.05–1.86) | |
IHD | 0.840 | ||||||
Event (%) | 162 (2.4) | 46 (2.4) | 21 (2.0) | 20 (2.6) | 7 (2.0) | 21 (2.7) | |
Person-years | 23,305 | 6407 | 3578 | 2492 | 1151 | 2764 | |
HR (95% CI) | 1.00 (Reference) | 1.09 (0.78–1.52) | 0.86 (0.54–1.36) | 1.24 (0.77–2.01) | 0.84 (0.39–1.80) | 1.09 (0.69–1.75) | |
Stroke | 0.034 | ||||||
Event (%) | 227 (3.3) | 49 (2.6) | 29 (2.7) | 29 (3.7) | 14 (4.0) | 42 (5.3) | |
Person-years | 23,142 | 6408 | 3580 | 2477 | 1137 | 2738 | |
HR (95% CI) | 1.00 (Reference) | 0.89 (0.65–1.22) | 0.92 (0.62–1.36) | 1.41 (0.95–2.10) | 1.28 (0.74–2.21) | 1.61 (1.14–2.26) |