Cases N = 716 (%) | Controls N = 757 (%) | OR (95%CI) a | p trend | |
---|---|---|---|---|
SMOKING STATUS b | ||||
Never smokers | 142 (19.8) | 341 (45.1) | Ref | |
Former smokers | 201 (28.1) | 246 (32.5) | 2.15 (1.62; 2.84) | |
Current smokers | 373 (52.1) | 170 (22.5) | 5.22 (3.96; 6.89) | |
INTENSITY, cigarettes/day | ||||
mean (SD)* | 18.5 (8.9) | 12.5 (9.2) | ||
Never smokers | 142 (19.8) | 341 (45.1) | Ref | |
< 10 | 80 (11.2) | 175 (23.2) | 1.11 (0.79; 1.56) | |
10–19 | 286 (39.9) | 150 (19.8) | 4.69 (3.52; 6.26) | |
20–29 | 148 (20.7) | 72 (9.5) | 5.40 (3.78; 7.70) | |
≥ 30 | 60 (8.4) | 18 (2.4) | 9.63 (5.37; 17.24) | < 0.001 |
Per 10 cigarettes/day | 2.27 (2.02; 2.56) | |||
DURATION OF TOBACCO SMOKING, years | ||||
mean (SD)* | 36.5 (11.6) | 26.4 (14.8) | ||
Never smokers | 142 (19.8) | 341 (45.1) | Ref | |
< 20 | 62 (8.7) | 150 (19.8) | 1.07 (0.74; 1.55) | |
20–29 | 74 (10.3) | 76 (10.1) | 2.19 (1.49; 3.23) | |
30–39 | 184 (25.7) | 94 (12.4) | 4.80 (3.46; 6.65) | |
≥ 40 | 254 (35.5) | 95 (12.6) | 7.43 (5.36; 10.30) | < 0.001 |
Per 10 years | 1.59 (1.49; 1.70) | |||
PACK-YEARS | ||||
mean (SD)* | 35.4 (21.0) | 18.5 (17.5) | ||
Never smokers | 142 (19.8) | 341 (45.1) | Ref | |
< 10 | 57 (8) | 173 (22.9) | 0.81 (0.56; 1.17) | |
10–19 | 83 (11.6) | 86 (11.4) | 2.40 (1.66; 3.48) | |
20–29 | 106 (14.8) | 58 (7.7) | 4.37 (2.97; 6.44) | |
≥ 30 | 328 (45.8) | 98 (13.0) | 9.16 (6.68; 12.54) | < 0.001 |
Per 10 pack-years | 1.65 (1.54; 1.76) | |||
TIME SINCE TOBACCO SMOKING CESSATION, years | ||||
mean (SD)* | 11.7 (10.7) | 24.0 (14.6) | ||
Never smokers | 142 (19.8) | 341 (45.1) | Ref | |
Current smokers | 373 (52.1) | 170 (22.5) | 5.30 (4.02; 7.00) | |
2–9 | 84 (11.7) | 45 (5.9) | 4.78 (3.14; 7.27) | |
10–19 | 65 (9.1) | 58 (7.7) | 2.78 (1.84; 4.20) | |
≥ 20 | 52 (7.3) | 143 (18.9) | 0.97 (0.66; 1.42) | < 0.001 |
Per 1 year (among ever smokers) | 0.94 (0.93; 0.96) | |||
CSI c | ||||
mean (SD)* | 1.6 (0.6) | 1.0 (0.7) | ||
Never smokers | 142 (19.8) | 341 (45.1) | Ref | |
< 0.69 | 67 (9.4) | 181 (23.9) | 0.98 (0.69; 1.39) | |
0.69–1.45 | 130 (18.2) | 116 (15.3) | 2.71 (1.95; 3.75) | |
1.46–1.95 | 173 (24.2) | 74 (9.8) | 5.69 (4.02; 8.04) | |
≥ 1.96 | 204 (28.5) | 44 (5.8) | 12.64 (8.50; 18.80) | < 0.001 |
Per 1 CSI unit | 3.13 (2.71; 3.61) |