Table 2 Characteristics of case-control studies about blood NO
From: Nitric oxide in occurrence, progress and therapy of lung Cancer: a systemic review and meta-analysis
Year | Author | Country | Age matched | Sex matched | Smoking matched | Histology | Stage | Blood NO (μmol/L) | NOS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Control | Case | |||||||||||
Mean ± SD | n | Mean ± SD | n | |||||||||
1996 | Ma | China | Yes | Yes | NA | SCC, ADC, LCC, SCLC | NA | 34.8 ± 18.2 | 34 | 48.5 ± 15.8 | 28 | 5 |
1997 | Fan | China | Yes | Yes | NA | mixed (mainly SCC, ADC) | early + advanced | 29.32 ± 16.78 | 25 | 58.75 ± 19.63 | 25 | 5 |
1998 | Li | China | NA | Yes | NA | SCC, ADC, SCLC | early + advanced | 42.10 ± 17.22 | 18 | 91.78 ± 47.25 | 25 | 6 |
1998 | Yu | China | Yes | Yes | NA | SCC, ADC | early + advanced | 5.80 ± 1.00 | 30 | 7.11 ± 1.35 | 46 | 6 |
1999 | Wu | China | Yes | Yes | NA | SCC, ADC, SCLC | early + advanced | 29.6 ± 11.4 | 30 | 37.8 ± 14.1 | 30 | 7 |
1999 | Yu | China | Yes | Yes | NA | SCC, ADC | early | 5.82 ± 1.31 | 25 | 9.91 ± 1.03 | 18 | 6 |
2001 | Bao | China | No | No | NA | SCC, ADC, SCLC | early + advanced | 67.64 ± 32.05 | 40 | 53.22 ± 26.08 | 57 | 6 |
2001 | Song | China | NA | Yes | NA | SCC, ADC, SCLC | early + advanced | 3.45 ± 0.94 | 28 | 4.93 ± 2.58 | 30 | 6 |
2001 | Zhu | China | No | No | NA | SCC, ADC, SCLC | early + advanced | 84.69 ± 12.10 | 17 | 119.37 ± 13.91 | 40 | 5 |
2001 | zheng | China | Yes | Yes | NA | SCC, ADC, LCC, SCLC | early + advanced | 73.42 ± 13.56 | 30 | 49.42 ± 18.78 | 40 | 6 |
2002 | Wu | China | NA | NA | NA | SCC, ADC, SCLC | early + advanced | 85.54 ± 39.63 | 20 | 48.69 ± 39.32 | 40 | 5 |
2002 | Wang | China | Yes | Yes | NA | SCC, ADC | early + advanced | 2.016 ± 0.524 | 36 | 5.902 ± 1.157 | 48 | 6 |
2002 | Shi | China | NA | Yes | NA | NA | NA | 2.012 ± 0.869 | 29 | 6.952 ± 2.571 | 17 | 6 |
2002 | Zhao | China | No | No | NA | SCC, ADC | early + advanced | 5.48 ± 1.06 | 60 | 7.38 ± 2.15 | 41 | 5 |
2002 | Liu | China | No | Yes | NA | NSCLC, SCLC | early + advanced | 49.3 ± 17.9 | 20 | 89.7 ± 25.0 | 70 | 6 |
2002 | Li | China | No | Yes | NA | SCC, ADC | NA | 5.24 ± 1.18 | 40 | 7.48 ± 1.65 | 30 | 6 |
2003 | Liu | China | Yes | No | NA | SCC, ADC | NA | 5.26 ± 1.14 | 50 | 8.65 ± 2.06 | 36 | 6 |
2003 | Yu | China | Yes | Yes | Yes | SCC, ADC | early + advanced | 78.38 ± 15.78 | 30 | 105.71 ± 25.68 | 30 | 7 |
2003 | Zhao | China | NA | Yes | NA | NA | early | 24.2 ± 10.4 | 35 | 60.4 ± 27.2 | 40 | 6 |
2004 | Tang | China | NA | Yes | NA | SCC, ADC, LCC | NA | 76.81 ± 16.61 | 40 | 122.3 ± 26.21 | 51 | 7 |
2005 | Fu | China | NA | Yes | NA | SCC, ADC, LCC | early + advanced | 44.2 ± 15.0 | 20 | 237.1 ± 21.0 | 82 | 7 |
2005 | Yin | China | Yes | Yes | NA | SCC, ADC, SCLC | early + advanced | 4.77 ± 1.81 | 10 | 35.59 ± 25.47 | 41 | 6 |
2005 | Chen | China | NA | NA | NA | NA | early | 68.5 ± 14.7 | 35 | 30.4 ± 12.9 | 31 | 5 |
2005 | Kaynar | Turkey | Yes | Yes | NA | NSCLC, SCLC | early + advanced | 43.4 ± 9.3 | 16 | 53.9 ± 8.8 | 32 | 6 |
2006 | Colakogullari | Turkey | NA | NA | NA | NSCLC, SCLC | advanced | 63.7 ± 32.2 | 15 | 93 ± 48 | 31 | 6 |
2006 | Li | China | Yes | Yes | NA | SCC, ADC | early + advanced | 54.6 ± 16.4 | 60 | 77.1 ± 22.3 | 62 | 6 |
2008 | Yan | China | NA | No | NA | NA | NA | 23.67 ± 6.18 | 30 | 21.97 ± 9.68 | 40 | 5 |
2008 | Esme | Turkey | Yes | No | Yes | SCC, ADC, LCC | early + advanced | 145.93 ± 27.03 | 20 | 211.32 ± 70.11 | 49 | 7 |
2009 | Long | China | NA | Yes | NA | SCC, ADC, LCC | NA | 77.81 ± 17.61 | 80 | 123.30 ± 25.21 | 100 | 6 |
2010 | Srivastava | India | Yes | Yes | NA | mainly SCC, ADC, LCC | advanced | 11.88 ± 3.48 | 144 | 25.76 ± 4.54 | 203 | 8 |
2012 | He | China | No | No | NA | SCC, ADC | early + advanced | 79.30 ± 10.88 | 50 | 125.89 ± 10.78 | 40 | 6 |
2014 | Zhang | China | Yes | Yes | Yes | NSCLC | NA | 16.79 ± 5.37 | 100 | 19.68 ± 4.11 | 110 | 9 |
2015 | Xu | China | NA | NA | NA | SCC, ADC, LCC, SCLC | NA | 68.4 ± 12.6 | 35 | 30.1 ± 11.7 | 36 | 5 |
2020 | Bayraktutan | Turkey | Yes | Yes | No | NSCLC, SCLC | NA | 24.03 ± 12.61 | 100 | 30.95 ± 18.20 | 100 | 8 |