Table 4 Univariable and multivariable analyses for having surgery, radiotherapy, systemic anticancer treatment or any treatment among colorectal cancer patients diagnosed in 2015–2016 in Norway

 2015

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 2016

0.96 [0.87,1.06]

0.95 [0.83,1.09]

0.97 [0.83,1.14]

0.87 [0.72,1.05]

1.16 [1.00,1.36]

1.03 [0.86,1.24]

1.03 [0.91,1.15]

1.02 [0.89,1.18]

 p-value

0.398

0.453

0.717

0.142

0.058

0.714

0.662

0.776

 18–49

1.17 [0.92,1.49]

1.20 [0.87,1.65]

0.77 [0.55,1.08]

0.84 [0.56,1.26]

0.80 [0.58,1.11]

0.83 [0.56,1.21]

1.06 [0.79,1.42]

1.05 [0.73,1.50]

 50–59

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 60–69

1.32 [1.11,1.56]

1.19 [0.95,1.49]

0.70 [0.55,0.88]

0.79 [0.59,1.05]

0.80 [0.64,1.00]

0.91 [0.69,1.19]

1.26 [1.02,1.56]

1.13 [0.88,1.46]

 70–79

1.91 [1.61,2.26]

1.71 [1.35,2.16]

0.40 [0.31,0.51]

0.49 [0.36,0.67]

0.49 [0.39,0.62]

0.59 [0.44,0.78]

1.53 [1.24,1.88]

1.24 [0.95,1.61]

 80–89

1.54 [1.29,1.84]

1.40 [1.09,1.80]

0.33 [0.25,0.44]

0.49 [0.34,0.69]

0.13 [0.09,0.19]

0.13 [0.09,0.20]

0.77 [0.63,0.95]

0.55 [0.42,0.72]

 90+

0.53 [0.41,0.69]

0.59 [0.40,0.88]

0.33 [0.19,0.57]

0.55 [0.28,1.08]

1.00 [1.00,1.00]

1.00 [1.00,1.00]

0.23 [0.18,0.31]

0.20 [0.14,0.29]

 p-value

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

 Female

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Male

0.80 [0.73,0.89]

0.90 [0.79,1.04]

1.49 [1.26,1.75]

0.98 [0.81,1.19]

1.35 [1.15,1.58]

1.22 [1.01,1.47]

0.88 [0.78,0.99]

0.97 [0.84,1.13]

 p-value

<0.001

0.159

<0.001

0.847

<0.001

0.036

0.028

0.706

 Localised

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Regional

0.39 [0.31,0.48]

0.27 [0.21,0.35]

4.10 [2.98,5.62]

7.32 [5.23,10.23]

6.45 [2.60,15.97]

6.73 [2.71,16.70]

0.43 [0.34,0.55]

0.32 [0.25,0.41]

 Metastasis

0.05 [0.04,0.07]

0.02 [0.02,0.03]

3.03 [2.13,4.31]

5.10 [3.50,7.44]

132.29 [54.64,320.28]

148.20 [60.96,360.32]

0.17 [0.13,0.21]

0.10 [0.08,0.14]

 Unknown

0.00 [0.00,0.00]

0.00 [0.00,0.00]

8.41 [5.85,12.11]

9.46 [6.34,14.13]

126.22 [51.52,309.22]

205.52 [83.21,507.62]

0.02 [0.02,0.03]

0.02 [0.01,0.02]

 p-value

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

 Single

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Married

1.16 [1.05,1.28]

1.04 [0.90,1.20]

1.09 [0.93,1.28]

1.00 [0.82,1.22]

1.38 [1.18,1.62]

1.23 [1.02,1.49]

1.45 [1.29,1.63]

1.20 [1.04,1.40]

 p-value

0.005

0.613

0.297

0.982

<0.001

0.030

<0.001

0.016

 Low

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Intermediate

1.05 [0.90,1.21]

1.04 [0.85,1.29]

1.08 [0.84,1.39]

0.91 [0.67,1.22]

1.09 [0.85,1.41]

1.12 [0.84,1.50]

1.10 [0.93,1.30]

1.13 [0.91,1.39]

 High

1.00 [0.84,1.18]

1.06 [0.83,1.35]

1.32 [1.01,1.74]

0.79 [0.56,1.11]

1.84 [1.41,2.41]

1.29 [0.93,1.78]

1.46 [1.20,1.78]

1.33 [1.03,1.72]

 p-value

0.682

0.894

0.051

0.339

<0.001

0.261

<0.001

0.078

 Southern and Eastern Norway

1.09 [1.04,1.14]

1.11 [1.04,1.18]

0.88 [0.82,0.95]

0.85 [0.77,0.93]

0.97 [0.90,1.04]

0.95 [0.88,1.04]

1.10 [1.04,1.16]

1.08 [1.01,1.15]

 Western Norway

0.81 [0.73,0.88]

0.71 [0.63,0.80]

1.09 [0.94,1.27]

1.05 [0.88,1.25]

1.40 [1.22,1.60]

1.59 [1.35,1.88]

0.91 [0.81,1.01]

0.89 [0.78,1.02]

 Central Norway

1.04 [0.92,1.17]

1.27 [1.07,1.52]

1.15 [0.96,1.38]

1.28 [1.03,1.60]

0.87 [0.71,1.05]

0.83 [0.66,1.04]

0.96 [0.84,1.11]

1.15 [0.97,1.37]

 Northern Norway

0.94 [0.81,1.09]

0.85 [0.70,1.04]

1.35 [1.09,1.67]

1.51 [1.15,1.97]

0.73 [0.57,0.95]

0.64 [0.47,0.85]

0.80 [0.68,0.94]

0.69 [0.57,0.85]

 p-value

<0.001

<0.001

0.002

<0.001

<0.001

<0.001

0.002

<0.001

 0

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 1

0.67 [0.61,0.75]

0.75 [0.64,0.88]

0.39 [0.31,0.49]

0.96 [0.73,1.26]

1.41 [1.20,1.66]

1.10 [0.90,1.35]

0.71 [0.63,0.81]

0.76 [0.64,0.89]

 p-value

<0.001

<0.001

<0.001

0.752

<0.001

0.345

<0.001

0.001

 No admissions

1.02 [0.79,1.34]

1.26 [0.87,1.83]

1.08 [0.73,1.60]

0.73 [0.46,1.14]

1.24 [0.86,1.78]

1.24 [0.79,1.94]

1.21 [0.87,1.69]

1.52 [1.01,2.29]

 0

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 1-2

1.09 [0.96,1.23]

1.15 [0.96,1.37]

0.66 [0.53,0.83]

0.97 [0.74,1.26]

0.67 [0.54,0.83]

0.72 [0.56,0.92]

0.91 [0.78,1.05]

0.96 [0.80,1.15]

 3+

0.77 [0.60,0.99]

0.92 [0.64,1.33]

0.57 [0.34,0.94]

0.89 [0.48,1.63]

0.16 [0.07,0.39]

0.16 [0.06,0.40]

0.47 [0.36,0.60]

0.51 [0.37,0.71]

 p-value

0.093

0.269

<0.001

0.566

<0.001

<0.001

<0.001

<0.001

 Rectum

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Colon

3.70 [3.33,4.11]

9.29 [7.88,10.96]

1.00 [1.00,1.00]

1.00 [1.00,1.00]

0.78 [0.66,0.91]

0.96 [0.78,1.17]

4.93 [4.36,5.56]

9.67 [8.21,11.39]

 p-value

<0.001

<0.001

0.002

0.672

<0.001

<0.001

 0

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 1

1.41 [1.24,1.59]

1.36 [1.14,1.62]

5.00 [3.47,7.20]

3.32 [2.22,4.97]

0.98 [0.80,1.19]

1.14 [0.90,1.45]

1.54 [1.34,1.77]

1.64 [1.37,1.97]

 p-value

<0.001

<0.001

<0.001

<0.001

0.814

0.282

<0.001

<0.001