Skip to main content

Table 1 Demographic Characteristics of the Study Population

From: Refinement of response assessment in neuro-oncology (RANO) using non-enhancing lesion type and contrast enhancement evolution pattern in IDH wild-type glioblastomas

 

Edema-dominant

NEL Group (n = 41)

Tumor-dominant

NEL Group (n = 45)

P

Age, years, median (range)

59 (31–81)

57 (31–77)

.362

No. of women patients (% of patients)

15 (36.6%)

22 (48.9%)

.253

KPS at baseline ≥70 (% of patients)

38 (92.7%)

40 (88.9%)

.548

MGMT promoter methylation (positive/negative/missing)

18/19/4

16/19/10

.285

Type of surgery (biopsy/STR/GTR)

0/4/37

3/12/30

.023

No. with pseudoprogression (% of patients)

21 (51.2%)

13 (28.9%)

.036

No. with true progression (% of patients)

20 (48.8%)

32 (71.1%)

.119

Median TTP, days

257 (95% CI: 205.9–305.5)

105 (95% CI: 98.5–153.6)

.042

  1. NEL non-enhancing lesion, IDH isocitrate dehydrogenase, KPS Karnofsky performance status, MGMT O6-methylguanine-DNA methyltransferase, STR subtotal resection, GTR gross total resection, CI confidence interval, TTP time to progression