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Fig. 4 | BMC Cancer

Fig. 4

From: Refinement of response assessment in neuro-oncology (RANO) using non-enhancing lesion type and contrast enhancement evolution pattern in IDH wild-type glioblastomas

Fig. 4

Prediction of TTP (A, B) and OS (C, D) based on NEL type and CE evolution pattern in patients with IDH wild-type glioblastoma. (A) Kaplan–Meier analysis of TTP in patients with edema-dominant type NEL stratified by CE evolution pattern (log-rank, P = .001). (B) Kaplan–Meier analysis of TTP in patients with tumor-dominant type NEL stratified by CE evolution pattern (log-rank, P = .528). (C) Kaplan–Meier analysis of OS in patients with edema-dominant type NEL stratified by CE evolution pattern (log-rank, P = .001). (D) Kaplan–Meier analysis of OS in patients with tumor-dominant type NEL stratified by CE evolution pattern (log-rank, P = .879). TTP = time to progression; OS = overall survival; NEL = non-enhancing lesion; CE = contrast enhancement; IDH = isocitrate dehydrogenase

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