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Table 3 Predictive value of EBV DNA for NPC development by different follow-up duration

From: Plasma Epstein-Barr virus DNA and risk of nasopharyngeal carcinoma in a prospective seropositive population

Variables

> 2 years

 

> 3 years

 

> 4 years

 
 

Adjusted HR(95%CIs)

P-value

Adjusted HR(95%CIs)

P-value

Adjusted HR(95%CIs)

P-value

≤3(undetectable)

Reference

 

Reference

 

Reference

 

> 3 (detectable)

10.878 (4.215–28.072)

< 0.0001a

5.139 (1.136–23.252)

0.0336a

4.054 (0.500–32.845)

0.1898a

> 3–999

9.637 (3.491–26.607)

< 0.0001b

2.785 (0.359–21.619)

0.3273b

4.472 (0.552–36.257)

0.3739b

≥1000

30.111 (3.662–247.587)

 

33.560 (3.996–281.872)

 

 
  1. aHRs are adjusted by sex, age, smoking status, NPC family history, salted food,education level; b P trend for the comparision among EBV DNA undetectable group, DNA levels at > 3–999 copies/ml and DNA levels ≥1000 copies/ml