Fig. 3

Time-dependent ROC analyses for survival prediction models. AUCs (%) in predicting progression or death risk of mCRPC patients over time were estimated and compared between a CTC only model and a model in combination of CTC and NLR (A for progression risk and B for death risk), or a model in combination of CTC and PLR (C for progression risk and D for death risk). ROC: receiver operating characteristic; AUC: area under the curve; mCRPC: metastatic castration-resistant prostate cancer; CTC: circulating tumor cell; NLR: neutrophil-lymphocyte ratio; PLR: platelet-lymphocyte ratio. Star indicates a P value of < 0.001 when comparing the AUC derived from a CTC only model and that from a combination model