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Fig. 7 | BMC Cancer

Fig. 7

From: ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genes

Fig. 7

Network protein interaction between cholesterol biosynthesis regulatory factors and their induction by A1542. a-g Q-RT-PCR analysis for the indicated cholesterol regulator genes in HEL cells treated with A1542 (1 μM) or control vehicle (DMSO) for 24 h. h-k AP1 inhibitor Tan IIA (10 μM) blocks the expression of indicated cholesterol biosynthesis genes induced by A1542 (2 μM), as determined by Q-RT-PCR. l TanIIA treatment was unable to block expression of EGR1

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BMC Cancer

ISSN: 1471-2407

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