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Fig. 5 | BMC Cancer

Fig. 5

From: ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genes

Fig. 5

Identification of genes involved in cholesterol biosynthesis by RNAseq. a Heatmap of 67 genes regulated in HEL cells treated with A1542 (1 μM) for 24 h. b Network map of 67 genes induced by A1542 in HEL cells using String database. Clusters of C2-C5 and their link to cholesterol biosynthesis cluster (C1) are highlighted with circles and further described in methods

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