Fig. 3From: ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genesInhibition of leukemogenesis by cholesterol. a Newborn BALBc mice infected with F-MuLV were treated with cholesterol, 5 weeks post viral infection and plotted after all mice succumbed to leukemia. b,c Hematocrit values (b) and tumor volume (c) at the time of death. d Tumor inhibition by LDL and HDL versus control DMSO-treated leukemic mice. e,f Hematocrit (e) and spleen weight (f) of leukemic mice at the time of deathBack to article page