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Fig. 1 | BMC Cancer

Fig. 1

From: ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genes

Fig. 1

Cholesterol biosynthesis genes are induced by A1542 in leukemic cells. a Diagram of cholesterol biosynthesis pathway. b RNAseq data for cholesterol biosynthesis genes after treatment of HEL for 24 h with A1542. c Level of total cholesterol in HEL cells treated with A1542 (2uM) and DMSO for 24 h. d-e Q-RT-PCR analysis of indicated genes after A1542 treatment of HEL cells for 24 h versus vehicle (DMSO)

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BMC Cancer

ISSN: 1471-2407

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