From: Metastatic colo-rectal cancer: real life experience from an Indian tertiary care center
Variable | Number (%) of patients |
---|---|
Median Age (range) years | 46 (11–82) |
Gender (Male / Female) | 219 (58%) / 158 (42%) |
Age ≤ 40 yrs. and ≥ 65 yrs. | 144 (38%) / 33 (8.8%) |
Median duration of symptoms, months | 6 (3–10) |
ECOG performance status (n = 320) | |
 0–1 | 223 (72%) |
 2–3 | 89 (28%) |
F/h of cancer / Gastrointestinal cancer (n = 320) | 38 (12%) / 17 (6%) |
Upfront Metastasis / Relapsed post adjuvant therapy | 256 (68%) / 121 (32%) |
Presenting symptoms (Up front metastasis) | |
 Abdominal pain or pain during defecation | 168 (65%) |
 Bleeding Per rectum | 148 (57%) |
 Altered bowel habits | 136 (52%) |
 Weight loss | 70 (27%) |
 Obstruction | 34 (13%) |
Laboratory parameters (median) | |
 Hemoglobin (n = 321) | 10.7 (9.3–12.3) |
 Platelets (n = 320) | 272,000 (18600–336,000) |
 Total leucocyte count (n = 320) | 7850 (6400–9500) |
 Albumin (n = 317) | 3.9 (3.6–4.4) |
 CEA (ng/ml) (median, n = 293) | 22 (5–117) |
High CEA level (> 5 ng/ml) | 228 (78%) |
High Serum alkaline phosphatase (n = 307) | 11 (3.6%) |
Grade (n = 342) | |
 Well / Moderately | 323 (94%) |
 Poorly differentiated | 19 (6%) |
Morphology (n = 325) | |
 Adenocarcinoma NOS | 216 (66%) |
 Signet ring | 30 (9.2%) |
 Mucinous | 78 (24%) |
 Adenosquamous | 1 (0.3%) |