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Table 1 Baseline characteristics, Pathology

From: Metastatic colo-rectal cancer: real life experience from an Indian tertiary care center

Variable

Number (%) of patients

Median Age (range) years

46 (11–82)

Gender (Male / Female)

219 (58%) / 158 (42%)

Age ≤ 40 yrs. and ≥ 65 yrs.

144 (38%) / 33 (8.8%)

Median duration of symptoms, months

6 (3–10)

ECOG performance status (n = 320)

 0–1

223 (72%)

 2–3

89 (28%)

F/h of cancer / Gastrointestinal cancer (n = 320)

38 (12%) / 17 (6%)

Upfront Metastasis / Relapsed post adjuvant therapy

256 (68%) / 121 (32%)

Presenting symptoms (Up front metastasis)

 Abdominal pain or pain during defecation

168 (65%)

 Bleeding Per rectum

148 (57%)

 Altered bowel habits

136 (52%)

 Weight loss

70 (27%)

 Obstruction

34 (13%)

Laboratory parameters (median)

 Hemoglobin (n = 321)

10.7 (9.3–12.3)

 Platelets (n = 320)

272,000 (18600–336,000)

 Total leucocyte count (n = 320)

7850 (6400–9500)

 Albumin (n = 317)

3.9 (3.6–4.4)

 CEA (ng/ml) (median, n = 293)

22 (5–117)

High CEA level (> 5 ng/ml)

228 (78%)

High Serum alkaline phosphatase (n = 307)

11 (3.6%)

Grade (n = 342)

 Well / Moderately

323 (94%)

 Poorly differentiated

19 (6%)

Morphology (n = 325)

 Adenocarcinoma NOS

216 (66%)

 Signet ring

30 (9.2%)

 Mucinous

78 (24%)

 Adenosquamous

1 (0.3%)

  1. CEA carcinoembryonic antigen, NOS not otherwise specified