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Table 3 Determinants of the late access (after first surgery) or no access to sarcoma specialized MTB within Netsarc+ from 2011 to 2014 (source: IGéAS cohort, RRePS – ResOs – NETSARC databases)

From: Determinants of the access to remote specialised services provided by national sarcoma reference centres

  

Univariate (N = 18,264)

Multivariate (N = 18,264)

Variables

late or no access / early access

OR

IC 95%

p-value

OR

IC 95%

p-value

Individual and clinical variables

Sex

0.0093

   

  Male

6421/2797

1

     

  Female

6460/2586

1.08

[1.02;1.16]

    

Age

< 0.0001

  

< 0.0001

  [18–25]

335/299

1

  

1

  

  [25–50]

2988/1507

1.77

[1.49;2.09]

 

1.33

[1.10;1.60]

 

  [50–75]

6286/2516

2.23

[1.89;2.62]

 

1.65

[1.38;1.99]

 

   > =75

3272/1061

2.75

[2.32;3.26]

 

1.85

[1.52;2.25]

 

Year of diagnosis

< 0.0001

  

< 0.0001

  2011

2972/944

1

  

1

  

  2012

3034/1173

0.82

[0.74;0.90]

 

0.78

[0.70;0.87]

 

  2013

3390/1576

0.68

[0.62;0.75]

 

0.79

[0.71;0.88]

 

    2014

3485/1690

0.65

[0.59;0.71]

 

0.68

[0.61;0.75]

 

Type of tumour

< 0.0001

  

< 0.0001

  Soft tissue

8187/4073

1

  

1

  

  Bone

415/637

0.32

[0.28;0.36]

 

0.35

[0.29;0.42]

 

  Viscera – GIST

2190/247

4.41

[3.84;5.05]

 

1.99

[1.32;3.00]

 

  Viscera - No GIST

2089/426

2.44

[2.18;2.72]

 

3.56

[3.16;4.01]

 

Depth of tumour

< 0.0001

  

< 0.0001

  Superficial and deep

667/377

1

  

1

  

  Superficial

3312/590

3.17

[2.721;3.7]

 

2.15

[1.83;2.54]

 

  Deep

7903/3835

1.16

[1.02;1.32]

 

0.82

[0.71;0.95]

 

  Missing

999/581

0.97

[0.82;1.14]

 

1.35

[1.09;1.66]

 

Size of tumour

< 0.0001

  

< 0.0001

   > =200

707/641

1

  

1

  

   [50–200]

5242/3070

1.54

[1.37;1.73]

 

1.40

[1.24;1.59]

 

   [0–50]

4486/1044

3.89

[3.43;4.42]

 

2.58

[2.23;2.98]

 

  Missing

2446/628

3.53

[3.07;4.05]

 

2.80

[2.39;3.28]

 

Histotype category

< 0.0001

  

< 0.0001

  Sarcoma

6809/4027

1

  

1

  

  GIST

2323/281

4.88

[4.29;5.56]

 

1.43

[0.96;2.14]

 

  Tumour of intermediate malignancy

3749/1075

2.06

[1.90;2.23]

 

2.07

[1.87;2.30]

 

Grade

< 0.0001

  

< 0.0001

  1

1204/746

1

  

1

  

  2

4373/1723

1.57

[1.41;1.75]

 

1.01

[0.90;1.10]

 

  3

1771/1382

0.79

[0.70;0.89]

 

0.92

[0.81;1.05]

 

  Not applicable

1304/808

1

[0.88;1.13]

 

0.94

[0.81;1.10]

 

  Missing

4229/724

3.61

[3.20;4.08]

 

2.59

[2.22;3.02]

 

Geographical variables

    

Region

< 0.0001

  

< 0.0001

  Auvergne-Rhône-Alpes

1556/776

1

  

1

  

  Grand-Est

1051/519

1.01

[0.88;1.15]

 

0.91

[0.78;1.06]

 

  Nouvelle-Aquitaine

1457/634

1.14

[1.00;1.30]

 

0.93

[0.81;1.08]

 

  Bourgogne-Franche-Comté

594/277

1.06

[0.90;1.26]

 

0.94

[0.78;1.13]

 

  Centre-Val de Loire

484/219

1.10

[0.91;1.32]

 

0.98

[0.80;1.20]

 

  Pays-de-la-Loire

718/318

1.12

[0.96;1.31]

 

0.98

[0.82;1.17]

 

  Occitanie

1242/561

1.10

[0.96;1.26]

 

1.05

[0.91;1.21]

 

  Hauts-de-France

1024/457

1.11

[0.97;1.28]

 

1.08

[0.93;1.27]

 

  Ile-de-France

1991/781

1.27

[1.12;1.43]

 

1.12

[0.97;1.29]

 

  Bretagne

761/237

1.60

[1.35;1.89]

 

1.31

[1.09;1.59]

 

  Normandie

420/168

1.24

[1.02;1.52]

 

1.34

[1.08;1.67]

 

  Provence-Alpes-Côte-d’Azur

1485/412

1.79

[1.56;2.06]

 

1.52

[1.31;1.77]

 

  Corse

98/24

2.03

[1.29;3.20]

 

1.57

[0.95;2.58]

 

GeoClasH classification of municipalities

0.1696

   

  Wealthy Metropolitan Areas

2763/1132

1

     

  Precarious Population Districts

6758/2827

0.97

[0.90;1.06]

    

Residential Outskirts

1586/721

0.90

[0.80;1.00]

    

  Agricultural and Industrial Plains

1122/428

1.07

[0.94;1.22]

    

  Rural Margins

652/275

0.97

[0.83;1.13]

    

Travel time to the closest sarcoma reference centre (in minutes, quintiles)

0.004

  

0.0013

   < = 29

2576/1168

1

  

1

  

  [ 29; 56]

2555/1069

1.08

[0.98;1.19]

 

1.12

[1.00;1.25]

 

  [ 56; 79]

2561/1122

1.03

[0.93;1.14]

 

1.07

[0.96;1.20]

 

  [ 79; 102]

2507/1009

1.12

[1.01;1.24]

 

1.21

[1.08;1.36]

 

   > 102

2682/1015

1.19

[1.08;1.32]

 

1.24

[1.10;1.40]

 

European Deprivation Index (quintiles)

0.04

   

   < = − 1.3 (least deprived)

2551/1115

1

     

  [-1.3; 1.8]

2527/1086

1.01

[0.92;1.12]

    

  [1.8; 5.6]

2648/1038

1.11

[1.00;1.23]

    

  [5.6; 9.2]

2584/1135

0.99

[0.90;1.09]

    

  > 9.2 (most deprived)

2571/1009

1.11

[1.00;1.23]

    

Population density (number of inhabitants/km2, quintiles)

0.8876

   

   < = 94.0926

2579/1089

1

     

  [ 94.0926; 306.127]

2541/1084

0.99

[0.89;1.09]

    

  [ 306.127; 1034.61]

2566/1080

1.00

[0.90;1.10]

    

  [ 1034.61; 3693.94]

2597/1054

1.04

[0.94;1.15]

    

   > 3693.94

2598/1076

1.02

[0.92;1.12]

    

APL index (spatial accessibility to general practitioners, quintiles)

0.8087

   

   < = 49.1 (lowest accessibility)

2546/1076

1

     

  [ 49.1; 64]

2575/1105

0.98

[0.89;1.08]

    

  [ 64; 78.4]

2517/1033

1.03

[0.93;1.14]

    

  [ 78.4; 90.7]

2666/1082

1.04

[0.94;1.15]

    

   > 90.7 (highest accessibility)

2577/1087

1.00

[0.90;1.10]