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Table 2 Univariate and multivariate cox analyses to evaluate the prognostic factors for OS

From: A new nomogram and risk classification system for predicting survival in small cell lung cancer patients diagnosed with brain metastasis: a large population-based study

Variable

Univariate analyses

Multivariate analyses

HR

95% CI

P

HR

95% CI

P

Age

  

< 0.001

   

 30–49

Reference

  

Reference

  

 50–69

1.146

0.928–1.414

0.205

1.198

0.969–1.480

0.095

 ≥ 70

1.626

1.310–2.019

< 0.001

1.767

1.421–2.198

< 0.001

Race

  

0.060

   

 White

Reference

  

Reference

  

 Black

1.000

0.873–1.144

0.997

0.962

0.839–1.103

0.579

 Others

0.776

0.630–0.955

0.016

0.734

0.595–0.905

0.004

Sex

  

0.030

   

 Male

Reference

  

Reference

  

 Female

0.911

0.837–0.992

0.0311

0.887

0.8135–0.966

0.006

T stage

  

< 0.001

   

 T0

Reference

  

Reference

  

 T1

1.449

0.970–2.164

0.070

1.343

0.898–2.008

0.151

 T2

1.582

1.074–2.330

0.020

1.451

0.984–2.140

0.060

 T3

1.830

1.242–2.698

0.002

1.664

1.127–2.456

0.010

 T4

1.775

1.210–2.603

0.003

1.623

1.104–2.387

0.014

N stage

  

< 0.001

   

 N0

Reference

  

Reference

  

 N1

0.964

0.795–1.168

0.707

0.931

0.768–1.129

0.469

 N2

1.242

1.090–1.414

0.001

1.230

1.079–1.402

0.002

 N3

1.236

1.068–1.431

0.005

1.220

1.052–1.415

0.009

Marriage

  

< 0.001

   

 Unmarried

Reference

  

Reference

  

 Married

0.862

0.792–0.938

< 0.001

0.851

0.780–0.928

< 0.001