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Table 3 Multivariable analysis to identify OS-related factors

From: Genetic alteration of Chinese patients with rectal mucosal melanoma

Variable

HR(95%CI)

P-value

Depth of tumor invasion

 

0.992

 Submucosa

1

 

 Muscularis propria

0.942 (0.237–3.745)

 

 Perirectal

1.023 (0.203–5.158)

 

Mitotic index

 

0.283

 ≤ 16

1

 

 > 16

1.819 (0.610–5.427)

 

Lymph node metastasis

 

0.045

 Absent

1

 

 Present

3.319 (1.026–10.737

 

 Unknown

–

 

Ulceration

 

0.084

 Absent

1

 

 Present

3.954 (0.830–18.842)

 

NRG1 Deletion

 

0.005

 No

1

 

 Yes

14.976 (2.305–97.300)

 

BRAF Mutation

 

0.007

 No

1

 

 Yes

7.732 (1.735–34.456)

 
  1. Factors considered in multivariable analysis were those with P-value < 0.1 in the result of univariate analysis
  2. HR hazard ratio, CI confidence interval
  3. Statistically significant P-values are bolded