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Table 2 Cumulative adverse events during treatment by maximum grade per patient

From: Survival benefit of induction chemotherapy for locally advanced nasopharyngeal carcinoma: prognosis based on a new risk estimation model

  IC + CCRT(n = 220) CCRT + AC (n = 170) IC + CCRT + AC(n = 339) P value
Leukopenia (Grade 3–4) 36a (16.4%) 54b (31.8%) 97 b(28.8%) 0.001
Skin reaction (Grade 3–4) 33a (15.1%) 27a (15.9%) 59a (17.4%) 0.742
Mucositis (Grade 3–4) 33a (16.3%) 26 a(15.3%) 67 a(20.0%) 0.332
Nausea or vomiting (Grade 2–3) 74 a(33.9%) 68a (40.2%) 103 a(30.7%) 0.100
  1. Grade 3–4 leukopenia, mucositis, and skin reactions, and grade 2–3 gastrointestinal reactions were recorded according to Common Terminology Criteria for Adverse Events (CTCAE) Version 4.0. Data were expressed as n or n(%); P value was calculated by chi-square test. Each subscript letter denotes a subset of treatment categories whose column proportions do not differ significantly from each other at the 0.05 level