Table 1 Clinical characteristics of nasopharyngeal carcinoma patients
|  | IC + CCRT(n = 220) | CCRT + AC (n = 170) | IC + CCRT + AC(n = 339) | P value |
|---|---|---|---|---|
Sex | ||||
 Male | 157 (71.4%) | 128 (75.3%) | 263 (77.6%) | 0.251 |
 Female | 63 (28.6%) | 42 (24.7%) | 76 (22.4%) |  |
Age group, years | ||||
  ≤ 55 | 164 a (74.5%) | 141 a,b (82.9%) | 296 b (87.3%) | 0.001 |
  > 55 | 56 a (25.5%) | 29 a,b (17.1%) | 43 b (12.7%) |  |
Staging | ||||
 III | 85 a (38.6%) | 88 b(51.8%) | 135 a (39.8%) | 0.033 |
 IVA | 112 a (50.9%) | 61 b (35.9%) | 162 a (47.8%) |  |
 IVB | 23 a(10.5%) | 21 a(12.4%) | 42 a(12.4%) |  |
EBV-DNA levels | ||||
  ≤ 1500 | 97 (54.8%) | 51 (46.8%) | 122 (51.3%) | 0.418 |
  > 1500 | 80 (45.2%) | 58 (53.2%) | 116 (48.7%) |  |
Smoking | ||||
 Yes | 91 (45.5%) | 61 (37.9%) | 137 (42.9%) | 0.339 |
 No | 109 (54.5%) | 100 (62.1%) | 182 (57.1%) |  |
Tumor category | ||||
 1 | 22 a (10.0%) | 21 a (12.4%) | 42 a (12.4%) | 0.040 |
 2 | 28 a (12.7%) | 40 b (23.5%) | 46 a (13.6%) |  |
 3 | 54 a (24.5%) | 39 a (22.9%) | 75 a (22.1%) |  |
 4 | 116 a (52.7%) | 70 a (41.2%) | 176 a (51.9%) |  |
Node category | ||||
 0 | 12 (5.5%) | 11 (6.5%) | 20 (5.9%) | 0.738 |
 1 | 54 (24.5%) | 43 (25.3%) | 66 (19.5%) |  |
 2 | 127 (57.7%) | 94 (55.3%) | 210 (61.9%) |  |
 3 | 27 (12.3%) | 22 (12.9%) | 43 (12.7%) |  |