Table 5 Comparison of the two patient groups by the number of genetic variants
From: Co-occurrence of thyroid and breast cancer is associated with an increased oncogenic SNP burden
BC only | BC and TC | p-value | |||
|---|---|---|---|---|---|
Mean | Std. error | Mean | Std. error | ||
Genes associated with BC | |||||
No. of SNPs with potential/ known association with BC | 0.27 | 0.12 | 0.84 | 0.22 | 0.029 |
No. of SNPs with potential/ known association with BC (weighted scores) | 0.17 | 0.08 | 0.53 | 0.15 | 0.039 |
112 cancer risk genes | |||||
No. of SNPs with no known association with oncogenesis | 1.20 | 0.30 | 0.74 | 0.20 | 0.206 |
No. of SNPs with a potential association with oncogenesis | 1.40 | 0.39 | 2.32 | 0.37 | 0.096 |
No. of SNPs with a known association with oncogenesis | 0.20 | 0.11 | 0.47 | 0.14 | 0.131 |
No. of SNPs with potential/ known association with oncogenesis | 1.60 | 0.36 | 2.79 | 0.39 | 0.032 |
No. of SNPs with potential and known association with oncogenesis (weighted scores) | 0.90 | 0.18 | 1.63 | 0.23 | 0.017 |