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Table 1 The Clinical characteristic baseline of CCRC patients in SEER

From: 53 years old is a reasonable cut-off value to define young and old patients in clear cell renal cell carcinoma: a study based on TCGA and SEER database

Characteristic

Before PSM

After PSM

Younger (<=53 y) N(%)

Older (> 53 y) N(%)

P

Younger (<=53 y) N(%)

Older (> 53 y) N(%)

P

Sex

  

< 0.001

  

0.613

 Male

9134 (63.98)

18,958 (59.81)

 

9124 (63.96)

9165 (64.24)

 

 Female

5142 (36.02)

12,740 (40.19)

 

5142 (36.04)

5101 (35.76)

 

Race

  

< 0.001

  

0.322

 Black

1020 (7.14)

1939 (6.12)

 

1014 (7.11)

1063 (7.45)

 

 White

12,199 (85.45)

27,428 (86.53)

 

12,195 (85.48)

12,105 (84.85)

 

 Other

1057 (7.40)

2331 (7.35)

 

1057 (7.41)

1098 (7.70)

 

Marital

  

< 0.001

  

0.739

 Single/Other

5124 (35.89)

10,484 (33.07)

 

5116 (35.86)

5143 (36.05)

 

 Married

9152 (64.11)

21,214 (66.93)

 

9150 (64.14)

9123 (63.95)

 

Size

  

< 0.001

  

0.571

 Dmax<=4 cm

7058 (49.44)

12,966 (40.90)

 

7052 (49.43)

6981 (48.93)

 

 4 cm < Dmax<=7 cm

3771 (26.41)

10,175 (32.10)

 

3771 (26.43)

3847 (26.97)

 

 Dmax> 7 cm

3447 (24.15)

8557 (27)

 

3443 (24.13)

3438 (24.10)

 

Grade

  

< 0.001

  

0.566

 I

2204 (15.44)

4226 (13.33)

 

2199 (15.41)

2243 (15.72)

 

 II

7893 (55.29)

16,362 (51.62)

 

7890 (55.31)

7873 (55.19)

 

 III

3376 (23.65)

8978 (28.32)

 

3375 (23.66)

3309 (23.20)

 

 IV

803 (5.62)

2132 (6.73)

 

802 (5.62)

841 (5.90)

 

Laterality

  

0.228

  

0.840

 Left

6949 (48.68)

15,622 (49.28)

 

6946 (48.69)

6963 (48.81)

 

 Right

7327 (51.32)

16,076 (50.72)

 

7320 (51.31)

7303 (51.19)

 

SEER historic stage A

  

< 0.001

  

0.754

 Localized

11,405 (79.89)

21,988 (69.37)

 

11,395 (79.88)

11,345 (79.52)

 

 Regional

1865 (13.06)

6576 (20.75)

 

1865 (13.07)

1892 (13.26)

 

 Distant

1006 (7.05)

3134 (9.89)

 

1006 (7.05)

1029 (7.21)

 

Radiation

  

0.035

  

0.202

 NO

13,967 (97.84)

30,909 (97.51)

 

13,960 (97.86)

13,928 (97.63)

 

 YES

309 (2.16)

789 (2.49)

 

306 (2.14)

338 (2.37)

 

Chemotherapy

  

< 0.001

  

0.274

 NO

13,664 (95.71)

29,986 (94.60)

 

13,655 (95.72)

13,617 (95.45)

 

 YES

612 (4.29)

1712 (5.40)

 

611 (4.28)

649 (4.55)