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Table 3 Drug-related adverse events occurring in any patient (%)

From: A phase I study of the safety and activity of K-001 in patients with advanced pancreatic ductal adenocarcinoma

Toxicity

Grade 1

Grade 2

Grade 3

Grade 4

Any Grade

Dyspepsia

1 (7.1)

2 (14.3)

0

0

3 (21.4)

Flatulence

1 (7.1)

1 (7.1)

0

0

2 (14.3)

Constipation

1 (7.1)

1 (7.1)

0

0

2 (14.3)

Haemorrhoids bleeding

1 (7.1)

1 (7.1)

0

0

2 (14.3)

Rash

0

1 (7.1)

0

0

1 (7.1)

ECG ST-T change

1 (7.1)

0

0

0

1 (7.1)

Dizzy

1 (7.1)

0

0

0

1 (7.1)

Diarrhea

1 (7.1)

0

0

0

1 (7.1)

Nausea

1 (7.1)

0

0

0

1 (7.1)

Total

8 (57.1)

6 (42.9)

0

0

14 (100.0)