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Fig. 2 | BMC Cancer

Fig. 2

From: CypB promotes cell proliferation and metastasis in endometrial carcinoma

Fig. 2

shRNA inhibited CypB expression efficiently in HEC-1-B cells, and CypB knockdown suppressed cell proliferation, colony formation, migration, and invasion in HEC-1-B cells. a shCYPB-1 and shCYPB-2 significantly downregulated the expression of CypB both in mRNA and protein level. The conventional microscope pictures of HEC-1-B cells treated with shNC or shRNAs (− 1 and − 2), and CCK-8 assay b, colony formation (c) assay, wound healing d, and transwell assays with matrigel (e) of HEC-1-B cells with CypB downregulation. This shows that CypB silencing significantly inhibited HEC-1-B cell proliferation and metastasis. (*p < 0.05, **p < 0.005)

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