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Table 5 Univariate and multivariate analysis of prognostic factors for overall survival

From: Induction chemotherapy combined with immunotherapy in locally advanced head and neck squamous cell carcinoma

Variables

Univariate

Cox model

Log-rank

p

HR[95%CI]

Age (< 40 vs ≥40)

0.324

  

Sex (Male vs female)

0.178

  

ECOG# (1vs 0)

0.023

0.007

1.889 [1.436–2.876]

Smoker

< 0.001

< 0.001

1.996 [1.432–3.443]

Drinker

0.435

  

Primary site (Hypopharynx vs others)

< 0.001

< 0.001

3.023 [1.764–6.443]

Tumor stage (T4 vs T2 + T3)

< 0.001

< 0.001

3.453 [2.000–7.546]

Neck stage (N+ vs N0)

< 0.001

< 0.001

2.653 [1.546–6.443]

Disease stage (IV vs III)

< 0.001

< 0.001

4.532 [2.335–13.345]

Immunotherapy

0.681

0.232

2.764 [0.887–5.437]

Curative method (surgery vs CRT)

< 0.001

< 0.001

2.213 [1.233–5.432]

  1. # ECOG Eastern Cooperative Oncology Group
  2. * CRT Chemoradiotherapy