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Table 4 Analysis by medical history. Mutations are reported according to personal and familial history for cancer

From: Comprehensive analysis of DNA damage repair genes reveals pathogenic variants beyond BRCA and suggests the need for extensive genetic testing in pancreatic cancer

 

Mutations

C4/C5

VUS

no

Personal history

 Yes

1

5

4

 No/unknown

7

10

33

Familial history

 Yes

4

5

14

 No/unknown

4

10

23

  1. C4/C5 Likely pathogenic (C4) or pathogenic (C5) according to the IARC classification, VUS Variants of uncertain significance
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BMC Cancer

ISSN: 1471-2407

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